Evidence map›Paper›PMID 32511001›Full record

ReviewCirculation2020

Advancing Research on the Complex Interrelations Between Atrial Fibrillation and Heart Failure: A Report From a US National Heart, Lung, and Blood Institute Virtual Workshop.

Sana M Al-Khatib, Emelia J Benjamin, Christine M Albert, Alvaro Alonso, Cynthia Chauhan, Peng-Sheng Chen, Anne B Curtis, Patrice Desvigne-Nickens, Jennifer E Ho, Carolyn S P Lam and 12 more

Abstract readReview
In one paragraph

Review in Circulation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Impact of vascular and cardiac parameters on quality of life in patients undergoing catheter ablation for atrial fibrillation.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Article
  6. Article
  7. Article
  8. Dynamic Increase of the CJournal of the American Heart Association · 2025
    Article
  9. Review
  10. The mCJACC. Advances · 2025
    Article
  11. Article
  12. Article
  13. Biomolecules & biomedicine · 2024
    Article
  14. Article
  15. Article
  16. Review
  17. Catheter ablation for patients with atrial fibrillation and heart failure with reduced and preserved ejection fraction: insights from the KiCS-AF multicentre cohort study.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Sana M Al-KhatibDivision of Cardiology and Duke Clinical Research Institute, Duke University Medical Center, Durham, NC (S.M.A.).
Emelia J BenjaminCardiovascular Medicine, Department of Medicine, Boston University School of Medicine, and Department of Epidemiology, Boston University School of Public Health, MA (E.J.B.).
Christine M AlbertDepartment of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA (C.M.A.).
Alvaro AlonsoDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (A.A.).
Cynthia ChauhanPatient representative, Wichita, KS (C.C.).
Peng-Sheng ChenThe Krannert Institute of Cardiology and Division of Cardiology, Department of Medicine, Indiana University School of Medicine, Indianapolis (P.-S.C.).
Anne B CurtisDepartment of Medicine, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, NY (A.B.C.).
Patrice Desvigne-NickensDivision of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (P.D.N., Y.R., L.S.C.).
Jennifer E HoCorrigan Minehan Heart Center, Cardiovascular Research Center and Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston (J.E.H.).
Carolyn S P LamNational Heart Centre Singapore and Duke-National University of Singapore (C.S.P.L.).
Mark S LinkDepartment of Medicine, Division of Cardiology, University of Texas Southwestern Medical Center, Dallas (M.S.L.).
Kristen K PattonDivision of Cardiology, University of Washington, Seattle (K.K.P.).
Margaret M RedfieldDepartment of Cardiovascular Medicine at Mayo Clinic, Rochester, MN (M.M.R.).
Michiel RienstraDepartment of Cardiology, University of Groningen, University Medical Center Groningen, The Netherlands (M.R., A.A.V.).
Yves RosenbergDivision of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (P.D.N., Y.R., L.S.C.).
Renate SchnabelDepartment of General and Interventional Cardiology, University Heart Center Hamburg, Germany, German Center for Cardiovascular Research, partner site Hamburg/Kiel/Luebeck (R.B.S.).
John A SpertusCardiovascular Division, Saint Luke's Mid America Heart Institute/University of Missouri-Kansas City, Kansas City, MO (J.A.S.).
Lynne Warner StevensonDivision of Cardiology, Vanderbilt University Medical Center, Nashville, TN (L.W.S.).
Mellanie True HillsStopAfib.org, American Foundation for Women's Health, Decatur, TX (M.T.H.).
Adriaan A VoorsDepartment of Cardiology, University of Groningen, University Medical Center Groningen, The Netherlands (M.R., A.A.V.).
Lawton S CooperDivision of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (P.D.N., Y.R., L.S.C.).
Alan S GoDivision of Research, Kaiser Permanente Northern California, Oakland (A.S.G.).

Funding

IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVALR01HL092577 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI BENJAMIN, EMELIA J., ELLINOR, PATRICK THOMAS · 2009 to 2025
$20.6M
ConProject-006U54HL120163 · NHLBI · AMERICAN HEART ASSOCIATION · PI BHATNAGAR, ARUNI, ROBERTSON, ROSE MARIE · 2018 to 2022
$18.8M
AFGen Consortium: Atrial Fibrillation Genomics to Functional AnalysesR01HL128914 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BENJAMIN, EMELIA J., ELLINOR, PATRICK THOMAS · 2015 to 2018
$3.1M
FHS-NEXT - Framingham Novel EXam using TechnologyR01HL141434 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BENJAMIN, EMELIA J., MCMANUS, DAVID D. · 2019 to 2022
$2.5M
Mentoring in patient-oriented atrial fibrillation and cardiovascular researchK24HL148521 · NHLBI · EMORY UNIVERSITY · PI ALONSO, ALVARO · 2019 to 2023
$593k
American Heart Association-American Stroke Association 16EIA26410001NHLBI NIH HHS K24 HL148521NHLBI NIH HHS R01 HL092577NHLBI NIH HHS R01 HL128914NHLBI NIH HHS R01 HL141434NHLBI NIH HHS U54 HL120163
6 · The paper itself

Abstract

The interrelationships between atrial fibrillation (AF) and heart failure (HF) are complex and poorly understood, yet the number of patients with AF and HF continues to increase worldwide. Thus, there is a need for initiatives that prioritize research on the intersection between AF and HF. This article summarizes the proceedings of a virtual workshop convened by the US National Heart, Lung, and Blood Institute to identify important research opportunities in AF and HF. Key knowledge gaps were reviewed and research priorities were proposed for characterizing the pathophysiological overlap and deleterious interactions between AF and HF; preventing HF in people with AF; preventing AF in individuals with HF; and addressing symptom burden and health status outcomes in AF and HF. These research priorities will hopefully help inform, encourage, and stimulate innovative, cost-efficient, and transformative studies to enhance the outcomes of patients with AF and HF.

Indexed as

Atrial FibrillationBiomedical ResearchEducationHeart FailureHumansNational Heart, Lung, and Blood Institute (U.S.)Observational Studies as TopicResearch ReportUnited Statesatrial fibrillationheart failureresearch

Identifiers

PMID32511001
PMCPMC7291844

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.