Evidence map›Paper›PMID 32510892›Full record

ArticleJBRA assisted reproduction2020

Morphokinetic parameters as auxiliary criteria for selection of blastocysts cultivated in a time-lapse monitoring system.

José Fernando de Macedo, Luiz Mauro Oliveira Gomes, Maristela Rodrigues Oliveira, Gustavo Capinzaiki Macedo, Giovanna Capinzaiki Macedo, Daniela Oliveira Gomes, Camila Dutra Souza Francisquini, Bruna Oliveira Ambrogi, Sandra Irene Sprogis Dos Santos

Abstract read
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Article in JBRA assisted reproduction, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

José Fernando de MacedoClínica Reproferty, São José dos Campos, SP, Brazil.
Luiz Mauro Oliveira GomesClínica Reproferty, São José dos Campos, SP, Brazil.
Maristela Rodrigues OliveiraClínica Reproferty, São José dos Campos, SP, Brazil.
Gustavo Capinzaiki MacedoClínica Reproferty, São José dos Campos, SP, Brazil.
Giovanna Capinzaiki MacedoClínica Reproferty, São José dos Campos, SP, Brazil.
Daniela Oliveira GomesClínica Reproferty, São José dos Campos, SP, Brazil.
Camila Dutra Souza FrancisquiniClínica Reproferty, São José dos Campos, SP, Brazil.
Bruna Oliveira AmbrogiClínica Reproferty, São José dos Campos, SP, Brazil.
Sandra Irene Sprogis Dos SantosUNIFUNVIC- Centro Universitário, Pindamonhangaba, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe embryonic profile up to blastocyst stage in a time-lapse system.

methodsA retrospective, longitudinal, analytical study of patients submitted to in vitro fertilization. The embryos were grouped according to the degree of expansion, internal cell mass and trophectoderm classification, the morphokinetic parameters were associated with the time periods stated in each evolution phase.

resultsThe appearance of a second polar corpuscle (CPap) occurred earlier in the embryos classified as excellent (2.99h; p<0.05), in relation to the embryos classified as good (3.40h), average (3.48h) and poor (3.55h). The embryos classified as excellent took less time for the pronuclei to disappear (PNbd) (21.80h; p<0.05), when compared to the good embryos (22.96h), the average (23.21h) and the poor (23.47h). As for the morphokinetic parameter, the end of the two-cell division (T2) occurred first in the excellent blastocysts (24.38h; p<0.05), when compared to the other groups: good (25.57h), average (25.53h) and poor (25.78h). With respect to synchronization with the division of three to four cells (S2), the poor embryos presented longer times for such division to occur (3.67h; p<0.05). When compared to the embryos from the groups excellent (1.97h), good (2.70h) and average (2.09h). At the time point of the blastocoel formation (TB), the excellent embryos (104.04h) did not differ from the good embryos (104.10h). However, when compared to average (107.27h) and poor (106.86h) embryos, there was statistical significance (p<0.05).

conclusionsEmbryos of better quality had a shorter time in some morphokinetic parameters when compared to the other groups, thus increasing the possibilities to establish new parameters for the classification and selection of embryos.

Indexed as

BlastocystEmbryo Culture TechniquesEmbryonic DevelopmentEmbryo TransferFemaleFertilization in VitroHumansRetrospective StudiesTime-Lapse Imagingblastocystblastocyst qualitytime-lapse monitoring system

Identifiers

PMID32510892
PMCPMC7558907

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