Evidence map›Paper›PMID 32510817›Full record

ReviewChemSusChem2020

An Introduction to Model Compounds of Lignin Linking Motifs; Synthesis and Selection Considerations for Reactivity Studies.

Ciaran W Lahive, Paul C J Kamer, Christopher S Lancefield, Peter J Deuss

Abstract readReview
In one paragraph

Review in ChemSusChem, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Butyl levulinate production from lignocellulose with mechanistic learning by hierarchical surrogate kinetic modelling.Green chemistry : an international journal and green chemistry resource : GC · 2026
    Article
  6. Oxygenation and Oxidation of Lignin Model Dimers by FungalJournal of the American Chemical Society · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Strategies Toward Synthesis and Conversion of Lignin Model Compounds.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Engineered Half-Unit-Cell MoSACS applied materials & interfaces · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ciaran W LahiveDepartment of Chemical Engineering (ENTEG), University of Groningen, Nijenborgh 4, 9747 AG, Groningen, Netherlands.ORCID http://orcid.org/0000-0002-1794-2921
Paul C J KamerSchool of Chemistry and Biomedical Science Research Complex, University of St. Andrews and EaStCHEM, North Haugh, St. Andrews, Fife, KY16 9ST, United Kingdom.ORCID http://orcid.org/0000-0002-9115-8844
Christopher S LancefieldSchool of Chemistry and Biomedical Science Research Complex, University of St. Andrews and EaStCHEM, North Haugh, St. Andrews, Fife, KY16 9ST, United Kingdom.ORCID http://orcid.org/0000-0001-9134-5589
Peter J DeussDepartment of Chemical Engineering (ENTEG), University of Groningen, Nijenborgh 4, 9747 AG, Groningen, Netherlands.ORCID http://orcid.org/0000-0002-2254-2500

Funding

Dutch TKI-BBEI TEBE11701Engineering and Physical Sciences Research Council EP/J018139/1FP7 People: Marie-Curie Actions ITN-GA-2013-60704Leverhulme Trust Early Career Fellowship ECF-2018-480
6 · The paper itself

Abstract

The development of fundamentally new valorization strategies for lignin plays a vital role in unlocking the true potential of lignocellulosic biomass as sustainable and economically compatible renewable carbon feedstock. In particular, new catalytic modification and depolymerization strategies are required. Progress in this field, past and future, relies for a large part on the application of synthetic model compounds that reduce the complexity of working with the lignin biopolymer. This aids the development of catalytic methodologies and in-depth mechanistic studies and guides structural characterization studies in the lignin field. However, due to the volume of literature and the piecemeal publication of methodology, the choice of suitable lignin model compounds is far from straight forward, especially for those outside the field and lacking a background in organic synthesis. For example, in catalytic depolymerization studies, a balance between synthetic effort and fidelity compared to the actual lignin of interest needs to be found. In this Review, we provide a broad overview of the model compounds available to study the chemistry of the main native linking motifs typically found in lignins from woody biomass, the synthetic routes and effort required to access them, and discuss to what extent these represent actual lignin structures. This overview can aid researchers in their selection of the most suitable lignin model systems for the development of emerging lignin modification and depolymerization technologies, maximizing their chances of successfully developing novel lignin valorization strategies.

Indexed as

biomassligninmodel compoundsorganic synthesis

Identifiers

PMID32510817
PMCPMC7540175

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.