Evidence map›Paper›PMID 32510480›Full record

ArticleJournal of visualized experiments : JoVE2020

Measurements of Physiological Stress Responses in C. Elegans.

Raz Bar-Ziv, Ashley E Frakes, Ryo Higuchi-Sanabria, Theodore Bolas, Phillip A Frankino, Holly K Gildea, Melissa G Metcalf, Andrew Dillin

Open access · greenAbstract readVideo-Audio Media
In one paragraph

Article in Journal of visualized experiments : JoVE, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 42 citations in OpenAlex.

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  10. Review
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  12. Distinct responses to non-autonomous UPRCommunications biology · 2025
    Article
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  16. Suppressing APOE4-induced neural pathologies by targeting the VHL-HIF axis.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Raz Bar-Ziv *Department of Molecular and Cell Biology, University of California, Berkeley.
Ashley E Frakes *Department of Molecular and Cell Biology, University of California, Berkeley.
Ryo Higuchi-Sanabria *Department of Molecular and Cell Biology, University of California, Berkeley.
Theodore BolasDepartment of Molecular and Cell Biology, University of California, Berkeley.
Phillip A FrankinoDepartment of Molecular and Cell Biology, University of California, Berkeley.
Holly K GildeaDepartment of Molecular and Cell Biology, University of California, Berkeley.
Melissa G MetcalfDepartment of Molecular and Cell Biology, University of California, Berkeley.
Andrew DillinDepartment of Molecular and Cell Biology, University of California, Berkeley; dillin@berkeley.edu.
University of California, Berkeley · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Neuroscience Training Program at UC BerkeleyT32NS095939 · NINDS · UNIVERSITY OF CALIFORNIA BERKELEY · PI BATEUP, HELEN S. · 2016 to 2025
$6.3M
Neuroendocrine Coordination of Mitochondrial Stress Signaling and ProteostasisR01ES021667 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI DILLIN, ANDREW G · 2012 to 2023
$4.6M
The Collapse of Proteostasis during Aging is Mediated by Cytoskeletal Actin FunctionsR01AG055891 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI DILLIN, ANDREW G · 2017 to 2021
$1.6M
Cell non-autonomous function of the unfolded protein responseR01AG042679 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI DILLIN, ANDREW G · 2013 to 2017
$1.5M
More than just a load control: cytoskeletal form and function during agingR00AG065200 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HIGUCHI-SANABRIA, RYO · 2021 to 2023
$747k
More than just a load control: cytoskeletal form and function during agingK99AG065200 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI HIGUCHI-SANABRIA, RYO · 2020 to 2021
$244k
Cell non-autonomous regulation of the unfolded protein response in agingF32AG051355 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI FRAKES, ASHLEY ELIZABETH · 2015 to 2017
$162k
Cell Non-Autonomous Signaling of the Unfolded Protein Response of the ER by Glial CellsF31AG060660 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI METCALF, MELISSA G · 2018 to 2021
$160k
NIA NIH HHS F31 AG060660NIA NIH HHS F32 AG051355NIA NIH HHS K99 AG065200NIA NIH HHS R00 AG065200NIA NIH HHS R01 AG042679NIA NIH HHS R01 AG055891NIEHS NIH HHS R01 ES021667NIH HHS P40 OD010440NINDS NIH HHS T32 NS095939
6 · The paper itself

Abstract

Organisms are often exposed to fluctuating environments and changes in intracellular homeostasis, which can have detrimental effects on their proteome and physiology. Thus, organisms have evolved targeted and specific stress responses dedicated to repair damage and maintain homeostasis. These mechanisms include the unfolded protein response of the endoplasmic reticulum (UPR

Indexed as

Heat-Shock ResponseOxidative StressStress, PhysiologicalUnfolded Protein ResponseAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsEndoplasmic ReticulumGreen Fluorescent ProteinsHomeostasisMitochondriaCaenorhabditis elegans Proteinsenhanced green fluorescent proteinGreen Fluorescent Proteins

Identifiers

PMID32510480
PMCPMC7840273
OpenAlexW3026818961

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.