ReviewDevelopmental cognitive neuroscience2020
Developmental trajectories to reduced activation of positive valence systems: A review of biological and environmental contributions.
Review in Developmental cognitive neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The effects of stress on reward responsiveness: a systematic review and preliminary meta-analysis of the event-related potential literature.Cognitive, affective & behavioral neuroscience · 2024Pooled it
- Self-injurious thoughts and behaviors and alterations in positive valence systems: A systematic review of the literature.Journal of psychiatric research · 2022Pooled it
- Parent Emotion Socialization and Positive Emotions in Child and Adolescent Clinical Samples: A Systematic Review and Call to Action.Clinical child and family psychology review · 2022Pooled it
- A pilot randomized controlled trial of a brief intervention targeting positive valence systems function to prevent internalizing symptoms in college students.Journal of consulting and clinical psychology · 2025Trial
- Targeting positive valence systems function in children of mothers with depressive symptoms: A pilot randomized trial of an RDoC-Informed preventive intervention.Behaviour research and therapy · 2023Trial
- Longitudinal associations between perceived stress and anhedonia during psychotherapy.Journal of affective disorders · 2023Trial
- Early parenting is associated with the development of neural reward responsiveness from childhood through adolescence.Communications psychology · 2026Article
- The interplay of reward responsiveness and socioeconomic disadvantage in the prospective prediction of depression symptoms in youth.Psychological medicine · 2025Article
- Emotion and Feeling in Parent-Child Dyads: Neurocognitive and Psychophysiological Pathways of Development.Children (Basel, Switzerland) · 2025Review
- Emotional Reactivity and Internalizing Symptoms in Middle Childhood: Integrating Autonomic and Behavioral Markers of Social Fear and Positive Affect.Developmental psychobiology · 2025Article
- Neuroimaging findings of adolescent depression: A review by the Research Domain Criteria (RDoC) framework.Psychiatry research. Neuroimaging · 2025Review
- Does Trauma Change the Way Individuals with Post-Traumatic Stress Disorder (PTSD) Deal with Positive Stimuli?Behavioral sciences (Basel, Switzerland) · 2024Article
- Neural Reactivity to Social Reward Moderates the Association Between Social Media Use and Momentary Positive Affect in Adolescents.Affective science · 2024Article
- Illuminating Hypomania in Early Adolescence: Associations Between Dark-Side and Bright-Side Hypomania, Insomnia, and Health-Related Quality of Life.Journal of clinical medicine · 2024Article
- Reward processes in extinction learning and applications to exposure therapy.Journal of anxiety disorders · 2024Review
- Relations Between Neighborhood Disadvantage and Electrocortical Reward Processing in Youth at High and Low Risk for Depression.Research on child and adolescent psychopathology · 2024Article
- Reduced reward responsiveness and depression vulnerability: Consideration of social contexts and implications for intervention.Psychophysiology · 2024Review
- Social Media Use as a Predictor of Positive and Negative Affect: An Ecological Momentary Assessment Study of Adolescents with and without Clinical Depression.Research on child and adolescent psychopathology · 2024Article
- Neural markers of emotion regulation difficulties in adolescent depression and risk for depression.Journal of mood and anxiety disorders · 2024Article
- Neural reward responsiveness and daily positive affect functioning in adolescent girls.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Reduced activation of positive valence systems (PVS), including blunted neural and physiological responses to pleasant stimuli and rewards, has been shown to prospectively predict the development of psychopathology. Yet, little is known about how reduced PVS activation emerges across development or what implications it has for prevention. We review genetic, temperament, parenting, and naturalistic and laboratory stress research on neural measures of PVS and outline developmentally-informed models of trajectories of PVS activation. PVS function is partly heritable and appears to reflect individual differences in early-emerging temperament traits. Although lab-induced stressors blunt PVS activation, effects of parenting and naturalistic stress on PVS are mixed and depend on the type of stressor, developmental timing, and interactions amongst risk factors. We propose that there may be multiple, dynamic developmental trajectories to reduced PVS activation in which combinations of genes, temperament, and exposure to severe, prolonged, or uncontrollable stress may exert direct and interactive effects on PVS function. Critically, these risk factors may alter PVS developmental trajectories and/or PVS sensitivity to proximal stressors. Distinct factors may converge such that PVS activation proceeds along a typical, accelerated, chronically low, or stress-reactive trajectory. Finally, we present directions for future research with translational implications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.