Evidence map›Paper›PMID 32510106›Full record

ArticleThe journal of nutrition, health & aging2020

Clinical Presentation of COVID19 in Dementia Patients.

A Bianchetti, R Rozzini, F Guerini, S Boffelli, P Ranieri, G Minelli, L Bianchetti, M Trabucchi

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of nutrition, health & aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 166 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
166citing papers in PubMed, 12 pooled it
25.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

166 citing papers in PubMed, 12 syntheses or guidelines pooled it, 326 citations in OpenAlex.

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  7. Dementia is a predictor for mortality outcome from coronavirus disease 2019 (COVID-19) infection.European archives of psychiatry and clinical neuroscience · 2021
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106 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

A BianchettiAngelo Bianchetti, MD. Department Medicine and Rehabilitation, Istituto Clinico S.Anna Hospital, via del Franzone 31, 25122 Brescia, Italy; e-mail: angelo.bianchetti@grupposandonato.it, https://orcid.org/0000-0002-2914-0627, phone: +390303197409 - fax: +390303198687.
R Rozzini
F Guerini
S Boffelli
P Ranieri
G Minelli
L Bianchetti
M Trabucchi
Ospedale Sant'Anna · ITFondazione Poliambulanza Istituto Ospedaliero · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveNo studies analyzing the role of dementia as a risk factor for mortality in patients affected by COVID-19. We assessed the prevalence, clinical presentation and outcomes of dementia among subjects hospitalized for COVID19 infection.

designRetrospective study.

settingCOVID wards in Acute Hospital in Brescia province, Northern Italy.

participantsWe used data from 627 subjects admitted to Acute Medical wards with COVID 19 pneumonia. MEASUREMENTS: Clinical records of each patients admitted to the hospital with a diagnosis of COVID19 infection were retrospectively analyzed. Diagnosis of dementia, modalities of onset of the COVID-19 infection, symptoms of presentation at the hospital and outcomes were recorded.

resultsDementia was diagnosed in 82 patients (13.1%). The mortality rate was 62.2% (51/82) among patients affected by dementia compared to 26.2% (143/545) in subjects without dementia (p<0.001, Chi-Squared test). In a logistic regression model age, and the diagnosis of dementia resulted independently associated with a higher mortality, and patients diagnosed with dementia presented an OR of 1.84 (95% CI: 1.09-3.13, p<0.05). Among patients diagnosed with dementia the most frequent symptoms of onset were delirium, especially in the hypoactive form, and worsening of the functional status.

conclusionThe diagnosis of dementia, especially in the most advanced stages, represents an important risk factor for mortality in COVID-19 patients. The clinical presentation of COVID-19 in subjects with dementia is atypical, reducing early recognition of symptoms and hospitalization.

Indexed as

BetacoronavirusAgedAged, 80 and overCoronavirus InfectionsCOVID-19DementiaFemaleHumansItalyLogistic ModelsMaleMiddle AgedPandemicsPneumonia, ViralPrevalenceRetrospective StudiesCOVID19 infectiondementiamortality risk

Identifiers

PMID32510106
PMCPMC7227170
OpenAlexW3024115442

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.