ArticleFrontiers in veterinary science2020
Toward Antibiotic Stewardship: Route of Antibiotic Administration Impacts the Microbiota and Resistance Gene Diversity in Swine Feces.
Article in Frontiers in veterinary science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 48 citations in OpenAlex.
- Pharmacokinetics of Long-Acting Ampicillin and Its Impact on the Gut Microbiome and Resistome in Rhesus Macaques (Macaca mulatta).Journal of veterinary pharmacology and therapeutics · 2026Article
- Genomic characterization of antimicrobial-resistance and virulence factors in Salmonella isolates obtained from pig farms in Antioquia, Colombia.PLoS neglected tropical diseases · 2025Article
- Florfenicol administration in piglets co-selects for multiple antimicrobial resistance genes.mSystems · 2024Article
- Article
- Metagenome-Assembled Genomes of Pig Fecal Samples in Nine European Countries: Insights into Antibiotic Resistance Genes and Viruses.Microorganisms · 2024Article
- Effect of single parenteral administration of marbofloxacin on bacterial load and selection of resistant Enterobacteriaceae in the fecal microbiota of healthy pigs.BMC veterinary research · 2024Article
- Effect of a probiotic and an antibiotic on the mobilome of the porcine microbiota.Frontiers in genetics · 2024Article
- Gut microbiota research nexus: One Health relationship between human, animal, and environmental resistomes.mLife · 2023Review
- The effects of antibiotic use on the dynamics of the microbiome and resistome in pigs.Animal microbiome · 2023Article
- Antimicrobial Resistance and Clonal Lineages ofAntibiotics (Basel, Switzerland) · 2023Review
- Molecular Detection of Metronidazole and Tetracycline Resistance Genes inAntibiotics (Basel, Switzerland) · 2023Article
- Affinity-Based Analysis Methods for the Detection of Aminoglycoside Antibiotic Residues in Animal-Derived Foods: A Review.Foods (Basel, Switzerland) · 2023Review
- Article
- Impact of Swine and Cattle Manure Treatment on the Microbial Composition and Resistome of Soil and Drainage Water.Microorganisms · 2022Article
- Cross-Sectional Survey of Antibiotic Resistance in Extended Spectrum β-Lactamase-ProducingAnimals : an open access journal from MDPI · 2022Article
- Antibiotic resistance and associated resistance determinants in differentVeterinary world · 2022Article
- Diversity of Antibiotic Resistance genes and Transfer Elements-Quantitative Monitoring (DARTE-QM): a method for detection of antimicrobial resistance in environmental samples.Communications biology · 2022Article
- Evaluation of the Impact of Antimicrobial Use Protocols in Porcine Reproductive and Respiratory Syndrome Virus-Infected Swine on Phenotypic Antimicrobial Resistance Patterns.Applied and environmental microbiology · 2022Article
- Article
- Impact of Antibiotic Therapies on Resistance Genes Dynamic and Composition of the Animal Gut Microbiota.Animals : an open access journal from MDPI · 2021Review
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oral antibiotics are a critical tool for fighting bacterial infections, yet their use can have negative consequences, such as the disturbance of healthy gut bacterial communities and the dissemination of antibiotic residues in feces. Altering antibiotic administration route may limit negative impacts on intestinal microbiota and reduce selective pressure for antimicrobial resistance genes (ARG) persistence and mobility. Thus, a study was performed in pigs to evaluate route of therapeutic oxytetracycline (oxytet) administration, an antibiotic commonly used in the U.S. swine industry, on intestinal microbial diversity and ARG abundance. Given that oral antibiotics would be in direct contact with intestinal bacteria, we hypothesized that oral administration would cause a major shift in intestinal bacterial community structure when compared to injected antibiotic. We further postulated that the impact would extend to the diversity and abundance of ARG in swine feces. At approximately 3 weeks-of-age, piglets were separated into three groups (
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.