Evidence map›Paper›PMID 32509787›Full record

ArticleFrontiers in cell and developmental biology2020

Xanthohumol Inhibits the Growth of Keratin 18-Overexpressed Esophageal Squamous Cell Carcinoma

Shuying Yin, Mengqiu Song, Ran Zhao, Xuejiao Liu, Woo Kyu Kang, Jeong Min Lee, Young Eun Kim, Chengjuan Zhang, Jung-Hyun Shim, Kangdong Liu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Pharmaceuticals (Basel, Switzerland) · 2025
    Review
  4. Article
  5. Review
  6. Anticancer Potential of Natural Chalcones: In Vitro and In Vivo Evidence.International journal of molecular sciences · 2023
    Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Honokiol Inhibits Melanoma Growth by Targeting Keratin 18Frontiers in cell and developmental biology · 2020
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 3 countries.

Shuying YinDepartment of Pathophysiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.
Mengqiu SongDepartment of Pathophysiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.
Ran ZhaoDepartment of Pathophysiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.
Xuejiao LiuDepartment of Pathophysiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.
Woo Kyu KangDepartment of Neurobiology, University of Massachusetts Medical School, Worcester, MA, United States.
Jeong Min LeeDepartment of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA, United States.
Young Eun KimTherapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon, South Korea.
Chengjuan ZhangThe Affiliated Cancer Hospital, Zhengzhou University, Zhengzhou, China.
Jung-Hyun ShimDepartment of Pharmacy, College of Pharmacy, Mokpo National University, Mokpo-si, South Korea.
Kangdong LiuDepartment of Pathophysiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.
Zigang DongDepartment of Pathophysiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.
Mee-Hyun LeeDepartment of Pathophysiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.
China-US (Henan) Hormel Cancer Institute · CNUniversity of Massachusetts Chan Medical School · USZhengzhou University · CNDongshin University · KRKorea Research Institute of Chemical Technology · KRMokpo National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Esophageal squamous cell carcinoma (ESCC) is a leading cause of cancer-related death worldwide. Xanthohumol is a prenylated flavonoid isolated from

Indexed as

cell growthesophageal squamous cell carcinoma (ESCC)keratin18protein stabilityxanthohumol

Identifiers

PMID32509787
PMCPMC7248302
OpenAlexW3024650037

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.