Evidence map›Paper›PMID 32509778›Full record

ArticleFrontiers in cell and developmental biology2020

Regulatory T Cell Extracellular Vesicles Modify T-Effector Cell Cytokine Production and Protect Against Human Skin Allograft Damage.

Sim Lai Tung, Giorgia Fanelli, Robert Ian Matthews, Jordan Bazoer, Marilena Letizia, Gema Vizcay-Barrena, Farid N Faruqu, Christina Philippeos, Rosalind Hannen, Khuloud T Al-Jamal and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 50 citations in OpenAlex.

  1. Review
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  4. Review
  5. Review
  6. Induced Treg-Derived Extracellular Vesicles Suppress CD4Journal of extracellular vesicles · 2025
    Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Comparison of different methods for isolating CD8Journal of extracellular biology · 2023
    Article
  15. Article
  16. Article
  17. Roles of Regulatory T Cell-Derived Extracellular Vesicles in Human Diseases.International journal of molecular sciences · 2022
    Review
  18. Review
  19. Review
  20. Extracellular Vesicles in Transplantation.Frontiers in immunology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Sim Lai TungImmunoregulation Laboratory, MRC Centre for Transplantation, School of Immunology & Microbial Sciences, King's College London, Guy's Hospital, London, United Kingdom.
Giorgia FanelliImmunoregulation Laboratory, MRC Centre for Transplantation, School of Immunology & Microbial Sciences, King's College London, Guy's Hospital, London, United Kingdom.
Robert Ian MatthewsSchool of Health, Sport and Bioscience, Stratford Campus, University of East London, London, United Kingdom.
Jordan BazoerSchool of Health, Sport and Bioscience, Stratford Campus, University of East London, London, United Kingdom.
Marilena LetiziaImmunoregulation Laboratory, MRC Centre for Transplantation, School of Immunology & Microbial Sciences, King's College London, Guy's Hospital, London, United Kingdom.
Gema Vizcay-BarrenaCentre for Ultrastructural Imaging, King's College London, London, United Kingdom.
Farid N FaruquInstitute of Pharmaceutical Science, Faculty of Life Sciences & Medicine, King's College London, London, United Kingdom.
Christina PhilippeosCentre for Stem Cells & Regenerative Medicine, King's College London, London, United Kingdom.
Rosalind HannenCentre for Cell Biology and Cutaneous Research, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.
Khuloud T Al-JamalInstitute of Pharmaceutical Science, Faculty of Life Sciences & Medicine, King's College London, London, United Kingdom.
Giovanna LombardiImmunoregulation Laboratory, MRC Centre for Transplantation, School of Immunology & Microbial Sciences, King's College London, Guy's Hospital, London, United Kingdom.
Lesley Ann SmythImmunoregulation Laboratory, MRC Centre for Transplantation, School of Immunology & Microbial Sciences, King's College London, Guy's Hospital, London, United Kingdom.
King's College London · GBGuy's Hospital · GBUniversity of East London · GBQueen Mary University of London · GB

Funding

British Heart Foundation RG/13/12/30395
6 · The paper itself

Abstract

Regulatory T cells (Tregs) are a subpopulation of CD4

Indexed as

allograft rejectioncytokinesextracellular vesiclesmiRNA – microRNARegulatory T (Treg) cells

Identifiers

PMID32509778
PMCPMC7251034
OpenAlexW3026677586

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.