ArticleFrontiers in chemistry2020
Exposure to Mycotoxin-Mixtures via Breast Milk: An Ultra-Sensitive LC-MS/MS Biomonitoring Approach.
Article in Frontiers in chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 48 citations in OpenAlex.
- Current status of human biomonitoring of beauvericin and enniatins.Archives of toxicology · 2026Review
- Climate-stressed crop mycobiomes as pre-harvest sentinels of human mycotoxin exposure: an AI-enabled One Health framework linking dysbiosis, exposomics, and toxicopathology.Frontiers in systems biology · 2026Review
- Human biomonitoring of mycotoxins: key challenges and future directions.Mycotoxin research · 2025Review
- Short-Term Exposure to Foodborne Xenoestrogens Affects Breast Cancer Cell Morphology and Motility Relevant for Metastatic BehaviorChemical research in toxicology · 2024Article
- Polyphenol exposure of mothers and infants assessed by LC-MS/MS based biomonitoring in breast milk.Analytical and bioanalytical chemistry · 2024Article
- Biomonitoring of Dietary Mycotoxin Exposure and Associated Impact on the Gut Microbiome in Nigerian Infants.Environmental science & technology · 2024Article
- Dietary mycotoxin exposure and human health risks: A protocol for a systematic review.Environment international · 2024Article
- Survey of the enniatins and beauvericin in raw and UHT cow's milk in Poland.Journal of veterinary research · 2023Article
- Longitudinal follow-up of zearalenone and deoxynivalenol mycotoxins in breast milk in the first five months of life.BMC pharmacology & toxicology · 2023Article
- Review
- Development and validation of a QuEChERS-LC-MS/MS method for determination of multiple mycotoxins in maize and sorghum from Botswana.Frontiers in fungal biology · 2023Article
- Trace analysis of emerging and regulated mycotoxins in infant stool by LC-MS/MS.Analytical and bioanalytical chemistry · 2022Article
- Article
- Review
- The Occurrence of Aflatoxins in Nuts and Dry Nuts Packed in Four Different Plastic Packaging from the Romanian Market.Microorganisms · 2020Article
- Review
- Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exposure to natural food contaminants during infancy may influence health consequences later in life. Hence, breast milk may serve as a vehicle to transport these contaminants, including mycotoxins, from mothers to their infants. Analytical methods mostly focused on single exposures in the past, thus neglecting co-occurrences and mixture effects. Here, we present a highly sensitive multi-biomarker approach by a sophisticated combination of steps during sample preparation including a Quick, Easy, Cheap, Effective, Rugged and Safe (QuEChERS) extraction followed by a solid phase extraction (SPE) cleanup and utilizing stable isotopes for compensating challenging matrix effects. The assay was validated in-house, reaching limits of detection (LOD) for all 34 analytes in the range of 0.1 to 300 ng/L with satisfying extraction efficiencies (75-109%) and stable intermediate precisions (1-18%) for most analytes. Compared to a similar multi-mycotoxin assay for breast milk, LOD values were decreased by a factor of 2-60x enabling the assessment of chronic low-dose exposures. The new method was applied to a small set of Nigerian breast milk samples (
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