ArticleJournal of family medicine and primary care2020
Long-term impacts of tonsillectomy on children's immune functions.
Article in Journal of family medicine and primary care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 19 citations in OpenAlex.
- Article
- Association between childhood tonsillectomy and increased risk of autoimmune disease: a nationwide population-based cohort study.Frontiers in medicine · 2026Article
- Surgical removal of Waldeyer's ring and long-term risk of Sjögren's syndrome: a population-based cohort study investigating the mucosal immune link.Frontiers in immunology · 2026Article
- Impact of Childhood Tonsillectomy on Adult Height-A Study of the UK Biobank.Laryngoscope investigative otolaryngology · 2025Article
- Engineering immune organoids to regenerate host immune system.Current opinion in genetics & development · 2024Review
- Article
- Review
- Awareness and Perceptions of the Impact of Tonsillectomy on the Level of Immunity and Autoimmune Diseases among the Adult Population in Abha City, Kingdom of Saudi Arabia.Healthcare (Basel, Switzerland) · 2023Article
- Age-related changes of the innate immune system of the palatine tonsil in a healthy cohort.Frontiers in immunology · 2023Article
- Comparison of perioperative indicators, treatment efficacy, and postoperative complications between tonsillotomy and tonsillectomy for children with obstructive sleep apnea hypopnea syndrome.Revista da Associacao Medica Brasileira (1992) · 2022Article
- Efficacy of obstructive sleep apnea treatment by antileukotriene receptor and surgery therapy in children with adenotonsillar hypertrophy: A descriptive and cohort study.Frontiers in neurology · 2022Article
- Anatomy and physiology of the palatine tonsils, adenoids, and lingual tonsils.World journal of otorhinolaryngology - head and neck surgery · 2021Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere exist a wide level of discrepancy regarding the role of tonsils and its indication among pediatricians and ENT specialists. This fact sometimes causes confusion and delay in making the right decisions by parents and specialists for appropriate treatment of patients.
objectivesThus, the aim of this study was to investigate the effects of long-term tonsillectomy on the immune system of patients.
methodsIn this case-control study we measured the status of immune system in 34 children (aged 9-15 years) following 4 to 6 years of tonsillectomy. We have also enrolled 30 healthy children with similar age group. Venous blood samples were taken and the serum levels of IgG, IgA, and IgM were detected along with expression of CD4, CD8, CD10 and CD56. Data were analyzed by SPSS version 18 software and a
resultsWe found that the mean serum levels IgM, IgA, and IgG in the case group was significantly (
conclusionOverall, according to these findings, CD10 as a marker of B lymphocytes in children undergoing tonsillectomy was significantly less than those healthy children. This may indicate a decrease in B cells and further reduced antibody production in these patients.
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Registered trials
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