Evidence map›Paper›PMID 32509212›Full record

ArticleAmerican journal of translational research2020

Prediction of therapeutic outcome and survival in a transgenic mouse model of pancreatic ductal adenocarcinoma treated with dendritic cell vaccination or CDK inhibitor using MRI texture: a feasibility study.

Aydin Eresen, Jia Yang, Junjie Shangguan, Yu Li, Su Hu, Chong Sun, Vahid Yaghmai, Al B Benson Iii, Zhuoli Zhang

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Aydin EresenDepartment of Radiology, Feinberg School of Medicine, Northwestern University Chicago, IL, USA.
Jia YangDepartment of Radiology, Feinberg School of Medicine, Northwestern University Chicago, IL, USA.
Junjie ShangguanDepartment of Radiology, Feinberg School of Medicine, Northwestern University Chicago, IL, USA.
Yu LiDepartment of Radiology, Feinberg School of Medicine, Northwestern University Chicago, IL, USA.
Su HuDepartment of Radiology, Feinberg School of Medicine, Northwestern University Chicago, IL, USA.
Chong SunDepartment of Radiology, Feinberg School of Medicine, Northwestern University Chicago, IL, USA.
Vahid YaghmaiDepartment of Radiology, Feinberg School of Medicine, Northwestern University Chicago, IL, USA.
Al B Benson IiiRobert H. Lurie Comprehensive Cancer Center of Northwestern University Chicago, IL, USA.
Zhuoli ZhangDepartment of Radiology, Feinberg School of Medicine, Northwestern University Chicago, IL, USA.
Northwestern University · USQingdao University · CN

Funding

MRI-Guided Dendritic-Cell-Based Vaccine Immunotherapy for Pancreatic CancerR01CA209886 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Vahid Yaghmai, Zhuoli Zhang · 2016 to 2026
$3.3M
Graduate Training Program for Magnetic Resonance ImagingT32EB025766 · NIBIB · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Michael Markl · 2019 to 2026
$1.6M
MRI-Guided Irreversible Electroporation Ablation for Liver TumorsR01CA196967 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ZHANG, ZHUOLI · 2015 to 2018
$1.4M
NCI NIH HHS R01 CA196967NCI NIH HHS R01 CA209886NIBIB NIH HHS T32 EB025766
6 · The paper itself

Abstract

There is a lack of a well-established approach for assessment of early treatment outcomes for modern therapies for pancreatic ductal adenocarcinoma (PDAC) e.g. dinaciclib or dendritic cell (DC) vaccination. Here, we developed multivariate models using MRI texture features to detect treatment effects following dinaciclib drug or DC vaccine therapy in a transgenic mouse model of PDAC including 21

Indexed as

Dendritic cell vaccinedinaciclibmachine learningmagnetic resonance imagingpancreatic ductal adenocarcinomatexture analysis

Identifiers

PMID32509212
PMCPMC7270001
OpenAlexW3033256196

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.