Evidence map›Paper›PMID 32508986›Full record

ReviewExperimental and therapeutic medicine2020

Beneficial effects of food supplements based on hydrolyzed collagen for skin care (Review).

Mihaela-Adi Lupu, Gratiela Gradisteanu Pircalabioru, Mariana-Carmen Chifiriuc, Radu Albulescu, Cristiana Tanase

Registry-linked trialOpen access · diamondAbstract readReview
In one paragraph

Review in Experimental and therapeutic medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06321770 (Oral Supplementation With Low Molecular Weight Collagen Peptides Improves Facial Wrinkles and Skin Hydration), which is not on this map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06321770 nacompletednot on this mapstarted 2024, after this paper: background citation

Oral Supplementation With Low Molecular Weight Collagen Peptides Improves Facial Wrinkles and Skin Hydration: Results From a Six-Week Randomized, Double-Blind, Placebo-Controlled Study

TypeinterventionalSponsorGala Servicios Clinicos S.L.Ran2024 to 2024Enrolled80ConditionsFacial Wrinkles, Skin HydrationArmsBioactive collagen peptides, Placebo
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. The Efficacy and Safety of CollaSel ProJournal of clinical medicine · 2024
    Article
  5. Review
  6. Article
  7. Comparison of Anti-Inflammatory and Antibacterial Properties ofInternational journal of molecular sciences · 2024
    Article
  8. Review
  9. Effects ofAntioxidants (Basel, Switzerland) · 2024
    Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Mihaela-Adi LupuSC Sanimed International Impex SRL, 087040 Bucharest, Romania.
Gratiela Gradisteanu PircalabioruSC Sanimed International Impex SRL, 087040 Bucharest, Romania.
Mariana-Carmen ChifiriucResearch Institute of University of Bucharest (ICUB), 050098 Bucharest, Romania.
Radu AlbulescuBiochemistry-Proteomics Department, Victor Babes National Institute of Pathology, 050096 Bucharest, Romania.
Cristiana TanaseBiochemistry-Proteomics Department, Victor Babes National Institute of Pathology, 050096 Bucharest, Romania.
Institutul National Victor Babes · ROUniversity of Bucharest · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ageing is a complex, multi-step process which involves, among others loss of collagen and elastin. Collagen is found in large amounts in the body, especially in the dermis layer. These fibers provide the skin's normal strength, hydration and mechanical properties. Collagen is largely available, as it can be extracted from many animal sources, it can be easily absorbed upon topical administration, hence it is largely used in the cosmetic and pharmaceutical industry for the treatment of premature aging. Bioactive peptides, such as collagen hydrolyzate, are among the most used ingredients for the development of nutraceuticals - food or food ingredients that have defined physiological effects. Numerous studies have demonstrated that peptides resulted from ingestion of hydrolysate collagen and detected in the blood stream have chemotactic properties for skin fibroblasts, helping the skin restoration process. The purpose of this minireview is to present an update on the use of hydrolyzed collagen for skin care.

Indexed as

hydrolyzed collagennutraceuticalspeptideskinwrinkles

Identifiers

PMID32508986
PMCPMC7271718
OpenAlexW2995339186

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.