Evidence map›Paper›PMID 32508919›Full record

ArticleInternational journal of endocrinology2020

Resistin Activates p65 Pathway and Reduces Glycogen Content through Keratin 8.

Fengyun Wen, Qiao Xia, Hui Zhang, Haipeng Shia, Amin Rajesh, Yanling Wu, Yi Yang, Zaiqing Yang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Fengyun WenCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471000, Henan, China.ORCID https://orcid.org/0000-0002-5938-5190
Qiao XiaKey Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, College of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070, Hubei, China.
Hui ZhangCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471000, Henan, China.
Haipeng ShiaCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471000, Henan, China.
Amin RajeshDepartment of Drug Discovery and Development, Harrison School of Pharmacy, Auburn University, 36849-5501 Auburn, Alabama, USA.
Yanling WuKey Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, College of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070, Hubei, China.
Yi YangKey Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, College of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070, Hubei, China.
Zaiqing YangCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471000, Henan, China.ORCID https://orcid.org/0000-0002-6160-9122
Henan University of Science and Technology · CNHuazhong Agricultural University · CNAuburn University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resistin is associated with metabolic syndrome and inflammatory conditions. Many studies have suggested that resistin inhibits the accumulation of glycogen; however, the exact mechanisms of resistin-induced decrease in glycogen content remain unclear. Keratin 8 is a typical epithelial intermediate filament protein, but numerous studies suggest a vital role of K8 in glucose metabolism. However, it is still not known whether K8 participates in the mediation of resistin-induced reduction of cellular glycogen accumulation. In this study, we found that resistin upregulated expression of the p65 subunit of NF-

Identifiers

PMID32508919
PMCPMC7251471
OpenAlexW3024953453

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.