Evidence map›Paper›PMID 32508604›Full record

ArticleFrontiers in behavioral neuroscience2020

Inhibition of Catechol-

Adrienne C DeBrosse, Abigail M Wheeler, James C Barrow, Gregory V Carr

Open access · goldAbstract read
In one paragraph

Article in Frontiers in behavioral neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Review
  3. Electrophysiological correlates of attention in the locus coeruleus-prelimbic cortex circuit during the rodent continuous performance test.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Article
  4. Article
  5. Effort-related decision making in humanized COMT mice: Effects of ValPharmacology, biochemistry, and behavior · 2020
    Article
  6. Inhibition of Catechol-Frontiers in behavioral neuroscience · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Adrienne C DeBrosseLieber Institute for Brain Development, Johns Hopkins University Medical Campus, Baltimore, MD, United States.
Abigail M WheelerDepartment of Pharmacology and Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, MD, United States.
James C BarrowLieber Institute for Brain Development, Johns Hopkins University Medical Campus, Baltimore, MD, United States.
Gregory V CarrLieber Institute for Brain Development, Johns Hopkins University Medical Campus, Baltimore, MD, United States.
Johns Hopkins University · USJohns Hopkins Medicine · USLieber Institute for Brain Development · US

Funding

Drug discovery of COMT inhibitors to treat cognitive deficits in schizophreniaR01MH107126 · NIMH · LIEBER INSTITUTE, INC. · PI BARROW, JAMES · 2015 to 2019
$4.1M
NIMH NIH HHS R01 MH107126
6 · The paper itself

Abstract

Effort-related choice (ERC) tasks allow animals to choose between high-value reinforcers that require high effort to obtain and low-value/low-effort reinforcers. Dopaminergic neuromodulation regulates ERC behavior. The enzyme catechol-

Indexed as

catechol-O-methyltransferasedopaminemotivationprefrontal cortextolcaponetouchscreen

Identifiers

PMID32508604
PMCPMC7253649
OpenAlexW3026670104

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.