Evidence map›Paper›PMID 32508571›Full record

ArticleFrontiers in neuroscience2020

7,8-Dihydroxyflavone Attenuates Alcohol-Related Behavior in Rat Models of Alcohol Consumption via TrkB in the Ventral Tegmental Area.

Xin-Xin Li, Tao Yang, Na Wang, Li-Li Zhang, Xing Liu, Yan-Min Xu, Qing Gao, Xiao-Feng Zhu, Yan-Zhong Guan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Xin-Xin LiDepartment of Physiology and Neurobiology, Mudanjiang Medical University, Mudanjiang, China.
Tao YangDepartment of Physiology and Neurobiology, Mudanjiang Medical University, Mudanjiang, China.
Na WangDepartment of Physiology and Neurobiology, Mudanjiang Medical University, Mudanjiang, China.
Li-Li ZhangDepartment of Physiology and Neurobiology, Mudanjiang Medical University, Mudanjiang, China.
Xing LiuDepartment of Physiology and Neurobiology, Mudanjiang Medical University, Mudanjiang, China.
Yan-Min XuDepartment of Physiology and Neurobiology, Mudanjiang Medical University, Mudanjiang, China.
Qing GaoDepartment of Physiology and Neurobiology, Mudanjiang Medical University, Mudanjiang, China.
Xiao-Feng ZhuDepartment of Physiology and Neurobiology, Mudanjiang Medical University, Mudanjiang, China.
Yan-Zhong GuanDepartment of Physiology and Neurobiology, Mudanjiang Medical University, Mudanjiang, China.
Mudanjiang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alcohol use disorder (AUD) is a ubiquitous substance use disorder in the world, of which neural mechanisms remain unclear. Alcohol consumption induces neuro-adaptations in the dopaminergic system originating from the ventral tegmental area (VTA), an important brain region for the reward function in AUD. Endogenous brain-derived neurotrophic factor (BDNF)-TrkB implicated in the development of neuroplasticity, including long-term potentiation of GABAergic synapses (LTP

Indexed as

78-Dihydroxyflavonealcohol-related behaviorBDNFTrkBventral tegmental area

Identifiers

PMID32508571
PMCPMC7248303
OpenAlexW3026998689

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.