ArticleeLife2020
Dreaming with hippocampal damage.
Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 46 citations in OpenAlex.
- Working Memory Deficits in Hippocampal Amnesia are Associated with Apathy.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- "I Can Code": An Innovative Workshop Introducing Students to Coding in the Context of Neuroscience Research.Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience · 2026Article
- Diencephalic integrity explains aspects of hippocampal amnesia.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Dreaming in patients with epilepsy: a cross-sectional cohort study.Journal of sleep research · 2025Article
- The Phenomenology of Offline Perception: Multisensory Profiles of Voluntary Mental Imagery and Dream Imagery.Vision (Basel, Switzerland) · 2025Article
- Dreaming conundrum.Journal of sleep research · 2025Review
- Why might animals remember? A functional framework for episodic memory research in comparative psychology.Learning & behavior · 2025Review
- We are the Sensors of Consciousness! A Review and Analysis on How Awakenings During Sleep Influence Dream Recall.Nature and science of sleep · 2025Article
- New strategies for the cognitive science of dreaming.Trends in cognitive sciences · 2024Review
- Ecological brain: reframing the study of human behaviour and cognition.Royal Society open science · 2024Review
- Nested compressed co-representations of multiple sequential experiences during sleep.Nature neuroscience · 2024Article
- The role of the human hippocampus in decision-making under uncertainty.Nature human behaviour · 2024Article
- Consciousness and sleep.Neuron · 2024Review
- Differential effects of bilateral hippocampal CA3 damage on the implicit learning and recognition of complex event sequences.Cognitive neuroscience · 2024Article
- A generative model of memory construction and consolidation.Nature human behaviour · 2024Article
- The generative grammar of the brain: a critique of internally generated representations.Nature reviews. Neuroscience · 2024Review
- Converging theories on dreaming: Between Freud, predictive processing, and psychedelic research.Frontiers in human neuroscience · 2023Review
- Article
- Circadian and Sleep Modulation of Dreaming in Women with Major Depression.Clocks & sleep · 2022Article
- Dream Recall/Affect and Cortisol: An Exploratory Study.Clocks & sleep · 2022Article
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Authors and funding
9 authors at 5 institutions in 3 countries.
Funding
Abstract
The hippocampus is linked with both sleep and memory, but there is debate about whether a salient aspect of sleep - dreaming - requires its input. To address this question, we investigated if human patients with focal bilateral hippocampal damage and amnesia engaged in dreaming. We employed a provoked awakening protocol where participants were woken up at various points throughout the night, including during non-rapid eye movement and rapid eye movement sleep, to report their thoughts in that moment. Despite being roused a similar number of times, dream frequency was reduced in the patients compared to control participants, and the few dreams they reported were less episodic-like in nature and lacked content. These results suggest that hippocampal integrity may be necessary for typical dreaming to occur, and aligns dreaming with other hippocampal-dependent processes such as episodic memory that are central to supporting our mental life.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.