ReviewThe journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians2022
Effectiveness and safety of available treatments for COVID-19 during pregnancy: a critical review.
Review in The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Maternal and Neonatal Outcomes in Pregnant Women Vaccinated Against COVID-19 Compared to an Unvaccinated Group.International journal of women's health · 2025Article
- Asymptomatic Children as a Missing Link in Preventing COVID-19 Transmission.Journal of research in health sciences · 2024Article
- Article
- COVID-19 and Pregnancy: An Updated Review about Evidence-Based Therapeutic Strategies.Journal of personalized medicine · 2023Review
- COVID-19 Model with High- and Low-Risk Susceptible Population Incorporating the Effect of Vaccines.Vaccines · 2022Article
- COVID-19 and Pregnancy: Have We Gotten through the Darkest Hour?Journal of personalized medicine · 2022Article
- Pregnancy and COVID-19.Journal of clinical medicine · 2022Review
- Clinical Manifestation and Obstetric Outcomes in Pregnant Women with SARS-CoV-2 Infection at Delivery: A Retrospective Cohort Analysis.Journal of personalized medicine · 2022Article
- Theaflavin 3-gallate inhibits the main protease (MScientific reports · 2022Article
- COVID-19 in pregnancy-what study designs can we use to assess the risk of congenital anomalies in relation to COVID-19 disease, treatment and vaccination?Paediatric and perinatal epidemiology · 2022Review
- Pregnancy and COVID-19, focus on vaccine and pharmacological treatment.Journal of reproductive immunology · 2022Review
- Managing COVID-19 in pregnant women.Breathe (Sheffield, England) · 2022Article
- Pharmacological Treatments against COVID-19 in Pregnant Women.Journal of clinical medicine · 2021Review
- Maternal and Fetal Outcomes of Pregnant Women Infected with Coronavirus Based on Tracking the Results of 90-Days Data in Hazrat -E- Rasoul Akram Hospital, Iran University of Medical Sciences.Bulletin of emergency and trauma · 2021Article
- SARS-CoV-2 infection during pregnancy and pregnancy-related conditions: Concerns, challenges, management and mitigation strategies-a narrative review.Journal of infection and public health · 2021Review
- Management and Prevention of COVID-19 in Pregnancy and Pandemic Obstetric Care: A Review of Current Practices.Healthcare (Basel, Switzerland) · 2021Review
- Inclusion of pregnant women in COVID-19 treatment trials: a review and global call to action.The Lancet. Global health · 2021Review
- Contracting COVID-19 in the first and second trimester of pregnancy: what we know - a concise qualitative systematic review.Archives of medical science : AMS · 2021Review
- Focusing Treatment on Pregnant Women With COVID Disease.Frontiers in global women's health · 2021Review
- Pregnancy and Childbirth in the COVID-19 Era-The Course of Disease and Maternal-Fetal Transmission.Journal of clinical medicine · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCOVID-19 is a pandemic disease caused by the SARS-CoV-2 and it spread globally in the last few months. The complete lack of specific treatment forced clinicians to use old drugs, chosen for their efficacy against similar viruses or their
methodsWe reviewed all the available literature concerning the drugs that have been used in the treatment of COVID-19 during pregnancy and whose safe assumption during pregnancy had been demonstrated by clinical studies (i.e. including studies on other infectious diseases). Drugs contra-indicated during pregnancy or with unknown adverse effects were not included in our review. RESULTS AND
conclusionsClinical trials are not often conducted among pregnant patients for safety reasons and this means that drugs that may be effective in general population cannot be used for pregnant women due to the lack of knowledge of side effects in this category of people .The choice to use a specific drug for COVID-19 in pregnancy should take into account benefits and possible adverse events in each single case. In the current situation of uncertainty and poor knowledge about the management of COVID-19 during pregnancy, this present overview may provide useful information for physicians with practical implications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.