Evidence map›Paper›PMID 32508067›Full record

ArticleJournal of Korean medical science2020

A Case of Consumptive Hypothyroidism in a 1-Month-Old Boy with Diffuse Infantile Hepatic Hemangiomas.

Young Ho Kim, Young Ah Lee, Choong Ho Shin, Kyung Taek Hong, Gi Beom Kim, Jae Sung Ko, Yun Jeong Lee

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of Korean medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Young Ho KimDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-5135-5296
Young Ah LeeDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0001-9179-1247
Choong Ho ShinDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-9813-1134
Kyung Taek HongDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-8822-1988
Gi Beom KimDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-7880-280X
Jae Sung KoDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-3064-2974
Yun Jeong LeeDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, Korea. yjlee103@snu.ac.kr.ORCID https://orcid.org/0000-0003-2847-2643
Seoul National University Children's Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Consumptive hypothyroidism is a rare paraneoplastic syndrome characterized by excessive inactivation of the thyroid hormones due to increased type 3 iodothyronine deiodinase activity of tumors. We report the case of severe consumptive hypothyroidism in a 1-month-old boy with infantile hepatic hemangiomas who presented with cardiac failure and cholestasis. Diffuse infiltration of hepatic hemangiomas was detected on abdominal imaging studies, and thyroid function screening test revealed severe hypothyroidism, which necessitated the administration of higher-than-usual doses of levothyroxine for the normalization of thyroid function. The patient was successfully treated with propranolol, prednisolone, and levothyroxine, and he showed normal thyroid function at 3 months of age and normal neurodevelopment at 9 months of age. This case highlights the importance of early recognition and prompt management of consumptive hypothyroidism in patients with infantile hepatic hemangiomas.

Indexed as

Adrenergic beta-AntagonistsAnti-Inflammatory AgentsCholestasisDrug Therapy, CombinationHeart FailureHemangiomaHumansHypothyroidismInfantIodide PeroxidaseLiverLiver NeoplasmsMalePrednisolonePropranololThyroid GlandAdrenergic beta-AntagonistsAnti-Inflammatory AgentsIodide Peroxidaseiodothyronine deiodinase type IIIPrednisolonePropranololThyroid HormonesThyroxineHypothyroidismInfantile Hepatic HemangiomaIodothyronine Deiodinase Type 3

Identifiers

PMID32508067
PMCPMC7279942
OpenAlexW3024391984

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.