ArticleThe Journal of veterinary medical science2020
The profile of urinary lipid metabolites in cats.
Article in The Journal of veterinary medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 5 citations in OpenAlex.
- Retrospective evaluation of lipiduria in urine from 140 dogs and 74 cats.Journal of veterinary internal medicine · 2026Article
- Review
- Urinary lipid production profile in canine patients with splenic mass.The Journal of veterinary medical science · 2022Article
- Comprehensive profiling of lipid metabolites in urine of canine patients with liver mass.The Journal of veterinary medical science · 2022Article
- The urinary lipid profile in cats with idiopathic cystitis.The Journal of veterinary medical science · 2022Article
- The profile of urinary lipid metabolites in healthy dogs.The Journal of veterinary medical science · 2022Article
- The profile of urinary lipid metabolites in cats with bacterial cystitis.The Journal of veterinary medical science · 2021Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polyunsaturated fatty acids including arachidonic acid (AA), docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), are converted to lipid mediators by oxidation. Unlike other mammals, cats cannot synthesize AA. Since their lipid metabolic features remain unknown, we qualitatively analyzed 118 types of urinary lipid metabolites in healthy neutered cats. Using LC-MS, we found 26 lipid metabolites in urines of all individuals. In detail, 20 AA-, 5 EPA- and 1 DHA-derived lipid mediators were detected. Focusing on oxidative pathway, 17 cyclooxygenase-metabolites and 5 metabolites produced by non-enzymatic pathway were detected. Of interest, few lipoxygenase- or cytochrome P450-metabolites were excreted. Thus, AA-derived cyclooxygenase-metabolites mainly composed the urinary lipid metabolites in cats.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.