Evidence map›Paper›PMID 32507787›Full record

ArticleExperimental animals2020

Involvement of NMDA receptors in tremor expression in Aspa/Hcn1 double-knockout rats.

Ai Nishitani, Haruna Nagayoshi, Shigeo Takenaka, Masahide Asano, Saki Shimizu, Yukihiro Ohno, Takashi Kuramoto

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental animals, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Ai NishitaniInstitute of Laboratory Animals, Graduate School of Medicine, Kyoto University, Yoshidakonoe-cho, Sakyo-ku, Kyoto 606-8501, Japan.
Haruna NagayoshiOsaka Institute of Public Health, 1-3-69 Nakamichi, Higashinari-ku, Osaka 537-0025, Japan.
Shigeo TakenakaDepartment of Clinical Nutrition, Graduate School of Comprehensive Rehabilitation, Osaka Prefecture University, 3-7-30 Habikino, Osaka 583-8555, Japan.
Masahide AsanoInstitute of Laboratory Animals, Graduate School of Medicine, Kyoto University, Yoshidakonoe-cho, Sakyo-ku, Kyoto 606-8501, Japan.
Saki ShimizuDepartment of Pharmacology, Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094, Japan.
Yukihiro OhnoDepartment of Pharmacology, Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094, Japan.
Takashi KuramotoInstitute of Laboratory Animals, Graduate School of Medicine, Kyoto University, Yoshidakonoe-cho, Sakyo-ku, Kyoto 606-8501, Japan.
Kyoto University · JPOsaka University of Pharmaceutical Sciences · JPOsaka Prefectural Institute of Public Health · JPOsaka Prefecture University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We recently demonstrated that aspartoacylase (Aspa) and hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 (Hcn1) genes were causative of essential tremor (ET) in rats. This finding was obtained using Aspa

Indexed as

AmidohydrolasesAnimalsBrainEssential TremorGene Knockout TechniquesHyperpolarization-Activated Cyclic Nucleotide-Gated ChannelsMolecular Targeted TherapyPhenolsPiperidinesPotassium ChannelsQuinoxalinesRats, Inbred F344Rats, Mutant StrainsReceptors, N-Methyl-D-AspartateSpinal Cord2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxalineAmidohydrolasesaspartoacylaseHcn1 protein, ratHyperpolarization-Activated Cyclic Nucleotide-Gated ChannelsNR2A NMDA receptorNR2B NMDA receptorPhenolsPiperidinesPotassium ChannelsQuinoxalinesReceptors, N-Methyl-D-AspartateRo 25-6981essential tremorgene knockoutNMDA receptorrat

Identifiers

PMID32507787
PMCPMC7677080
OpenAlexW3033812185

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.