Evidence map›Paper›PMID 32507410›Full record

ArticleEuropean annals of otorhinolaryngology, head and neck diseases2020

The influenza virus, SARS-CoV-2, and the airways: Clarification for the otorhinolaryngologist.

L de Gabory, A Alharbi, M Kérimian, M-E Lafon

Abstract read
In one paragraph

Article in European annals of otorhinolaryngology, head and neck diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Seawater nasal wash to reduce symptom duration and viral load in COVID-19 and upper respiratory tract infections: a randomized controlled multicenter trial.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Trial
  3. Article
  4. Review
  5. Review
  6. Review
  7. COVID-19 patient with recurrent anosmia and its impact on management.European annals of otorhinolaryngology, head and neck diseases · 2022
    Article
  8. Article
  9. Surgery under COVID: An observational study.European annals of otorhinolaryngology, head and neck diseases · 2022
    Observational
  10. Model Calculations of Aerosol Transmission and Infection Risk of COVID-19 in Indoor Environments.International journal of environmental research and public health · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

L de GaboryDepartment of ENT and Head & Neck Surgery, Bordeaux University Hospital, France; University Bordeaux, 33000 Bordeaux, France. Electronic address: ludovic.de-gabory@chu-bordeaux.fr.
A AlharbiDepartment of ENT and Head & Neck Surgery, Bordeaux University Hospital, France.
M KérimianDepartment of ENT and Head & Neck Surgery, Bordeaux University Hospital, France.
M-E LafonDepartment of Virology and Biological Monitoring Unit, Bordeaux University Hospital, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The influenza virus and SARS-CoV-2 cause trivial upper and severe lower respiratory infections (Influenza virus 290,000 to 650,000 deaths/year). These viruses come into contact with the airways either by direct projection, by secondary inhalation of airborne droplets, or by handling (fomites). The objective of this article is to clarify the mechanisms of production and penetration of droplets of secretions emitted during all expiratory phenomena likely to transport these viruses and come into contact with the respiratory mucosa. The droplets>5μm follow the laws of ballistics, those<5μm follow Brownian motion and remain suspended in the air. The aerosols of droplets are very heterogeneous whether the subject is healthy or sick. During an infectious period, not all droplets contain viral RNA. If these RNAs are detectable around patients, on surfaces, and in the ambient air at variable distances according to the studies (from 0.5m to beyond the patient's room), this is without prejudice to the infectious nature (viability) of the virus and the minimum infectious dose. There is a time lag between the patient's infectious period and that of RNA detection for both viruses. Subsequently, the inhaled particles must meet the laws of fluid dynamics (filtration) to settle in the respiratory tree. All of this partly explains the contagiousness and the clinical expression of these two viruses from the olfactory cleft to the alveoli.

Indexed as

OtolaryngologyAerosolsBetacoronavirusBodily SecretionsCoronavirus InfectionsCOVID-19HumansInfluenza, HumanOrthomyxoviridaePandemicsPneumonia, ViralRespiratory MucosaRNA, ViralSARS-CoV-2AerosolsRNA, ViralAirborne particleCOVID-19Influenza virusRespiratory infectionSARS-CoV-2

Identifiers

PMID32507410
PMCPMC7261469

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.