Evidence map›Paper›PMID 32507005›Full record

Observational studyVirulence2020

Measles in Romania - clinical and epidemiological characteristics of hospitalized measles cases during the first three years of the 2016-ongoing epidemic.

Daniela Pițigoi, Oana Săndulescu, Maria Dorina Crăciun, Anca Drăgănescu, Gheorghiță Jugulete, Anca Streinu-Cercel, Angelica Vișan, Claudia Rîciu, Alexandru Rafila, Victoria Aramă and 2 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Virulence, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Daniela PițigoiDepartment of Epidemiology, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy , Bucharest, Romania.ORCID 0000-0003-4118-8268
Oana SăndulescuNational Institute for Infectious Diseases "Prof. Dr. Matei Balș" , Bucharest, Romania.ORCID 0000-0002-2586-4070
Maria Dorina CrăciunDepartment of Epidemiology, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy , Bucharest, Romania.
Anca DrăgănescuNational Institute for Infectious Diseases "Prof. Dr. Matei Balș" , Bucharest, Romania.
Gheorghiță JuguleteNational Institute for Infectious Diseases "Prof. Dr. Matei Balș" , Bucharest, Romania.ORCID 0000-0002-4193-063X
Anca Streinu-CercelNational Institute for Infectious Diseases "Prof. Dr. Matei Balș" , Bucharest, Romania.ORCID 0000-0003-2794-6720
Angelica VișanNational Institute for Infectious Diseases "Prof. Dr. Matei Balș" , Bucharest, Romania.
Claudia RîciuNational Institute for Infectious Diseases "Prof. Dr. Matei Balș" , Bucharest, Romania.
Alexandru RafilaNational Institute for Infectious Diseases "Prof. Dr. Matei Balș" , Bucharest, Romania.ORCID 0000-0003-3796-5140
Victoria AramăNational Institute for Infectious Diseases "Prof. Dr. Matei Balș" , Bucharest, Romania.ORCID 0000-0002-1657-3642
Monica LuminosNational Institute for Infectious Diseases "Prof. Dr. Matei Balș" , Bucharest, Romania.
Adrian Streinu-CercelNational Institute for Infectious Diseases "Prof. Dr. Matei Balș" , Bucharest, Romania.ORCID 0000-0001-6382-5067
Carol Davila University of Medicine and Pharmacy · RONational Institute of Research and Development for Biological Sciences · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A large measles epidemic has been ongoing in Romania and many European countries, since 2016. We report case-based surveillance data for all patients (n = 1371) with laboratory-confirmed and epidemiologically-confirmed measles hospitalized in a major infectious diseases hospital in Bucharest Romania during the first three years of the current measles epidemic (July 2016-July 2019). More than half of the patients (57.6%) had ages below 5 years; 6% (n = 82) had preexisting comorbidities. Only 1.5% of the patients had been fully vaccinated, 5.9% had received only one vaccine dose, while 92.8% had not been vaccinated at all against measles. The rate of measles-related complications was 93.4%; complications occurred more frequently among patients who were not eligible for vaccination due to young age or underlying diseases, and among children, who developed pneumonia and enterocolitis more frequently than adults. The median hospital length-of-stay was 6 days. Eight cases (0.6%) required intensive care and mechanical ventilation, and three deaths (0.2%) were recorded. Measles disproportionately affects patient groups who are not eligible for vaccination. During the current epidemic in Romania, 98.5% of the patients hospitalized for measles had not been vaccinated and among these, 75.7% would have been eligible for vaccination. For the remaining pool of unvaccinated children, supplementary immunization activities are urgently needed.

Indexed as

Epidemiological MonitoringAdolescentAdultCase-Control StudiesChildChild, PreschoolComorbidityEpidemicsFemaleHospitalizationHumansInfantInfant, NewbornMaleMeaslesMiddle AgedMeaslesmeasles epidemicvaccinationvaccine-preventable disease

Identifiers

PMID32507005
PMCPMC7549973
OpenAlexW3033355087

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.