Trial reportPhysiological reports2020
Comparison of cerebrovascular reactivity recovery following high-intensity interval training and moderate-intensity continuous training.
Trial report in Physiological reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Physiological influences on neurovascular coupling: A systematic review of multimodal imaging approaches and recommendations for future study designs.Experimental physiology · 2025Pooled it
- Effects of high intensity interval exercise on cerebrovascular function: A systematic review.PloS one · 2020Pooled it
- Feasibility of superimposed supine cycling and lower body negative pressure as an effective means of prolonging exercise tolerance in individuals experiencing persisting post-concussive symptoms: Preliminary results.Experimental physiology · 2026Trial
- Comparison of cerebrovascular reactivity recovery following high-intensity interval training and moderate-intensity continuous training.Physiological reports · 2020Trial
- Shear-mediated dilation of the internal carotid artery is attenuated under hypocapnic conditions beyond reductions in shear stimulus.European journal of applied physiology · 2026Article
- An acute concurrent exercise bout better preserves cerebrovascular reactivity to hypocapnia than either resistance or aerobic exercise.European journal of applied physiology · 2026Article
- Physiological evaluation of the Calgary adapted aRm ergometer (CARE) concussion exertion test in adolescent athletes: A repeated-measures observational study.Experimental physiology · 2026Article
- CARE-ing for concussions: Development of the Calgary Adapted aRm Ergometer (CARE) exertion test: A physiological alternative to the Calgary Concussion Cycle Test.Experimental physiology · 2026Article
- Quantification of the cerebral pressure-flow relationship directional sensitivity: Reliability of shorter repeated squat-stand durations.Experimental physiology · 2026Article
- Whole-body hot water immersion effect on cerebral haemodynamics and subsequent cerebrovascular reactivity to carbon dioxide.Experimental physiology · 2025Article
- Systolic versus diastolic differences in cerebrovascular reactivity to hypercapnic and hypocapnic challenges.European journal of applied physiology · 2025Article
- Exercise intolerance and time to medical clearance to return to sport following sport-related concussion in adolescents.BMJ open sport & exercise medicine · 2025Article
- Challenging dynamic cerebral autoregulation across the physiological COExperimental physiology · 2025Article
- Lower dynamic cerebral autoregulation following acute bout of low-volume high-intensity interval exercise in chronic stroke compared to healthy adults.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Article
- Can Alterations in Cerebrovascular COJournal of clinical medicine · 2023Article
- The acute effect of exercise intensity on peripheral and cerebral vascular function in healthy adults.Journal of applied physiology (Bethesda, Md. : 1985) · 2022Article
- Neurovascular coupling on trial: How the number of trials completed impacts the accuracy and precision of temporally derived neurovascular coupling estimates.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022Article
- Effect of a speed ascent to the top of Europe on cognitive function in elite climbers.European journal of applied physiology · 2022Article
- Cerebrovascular response to an acute bout of low-volume high-intensity interval exercise and recovery in young healthy adults.Journal of applied physiology (Bethesda, Md. : 1985) · 2022Article
- Temporal evolution of neurovascular coupling recovery following moderate- and high-intensity exercise.Physiological reports · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A common inclusion criterion when assessing cerebrovascular (CVR) metrics is for individuals to abstain from exercise for 12-24 hr prior to data collections. While several studies have examined CVR during exercise, the literature describing CVR throughout post-exercise recovery is sparse. The current investigation examined CVR measurements in nine participants (seven male) before and for 8 hr following three conditions: 45-min moderate-continuous exercise (at ~50% heart-rate reserve), 25-min high-intensity intervals (ten, one-minute intervals at ~85% heart-rate reserve), and a control day (30-min quiet rest). The hypercapnic (40-60 mmHg) and hypocapnic (25-40 mmHg) slopes were assessed via a modified rebreathing technique and controlled stepwise hyperventilation, respectively. All testing was initiated at 8:00a.m. with transcranial Doppler ultrasound measurements to index cerebral blood velocity performed prior to the condition (pre) with serial follow-ups at zero, one, two, four, six, and eight hours within the middle and posterior cerebral artery (MCA, PCA). Absolute and relative MCA and PCA hypercapnic slopes were attenuated following high-intensity intervals at hours zero and one (all p < .02). No alterations were observed in either hypocapnic or hypercapnic slopes following the control or moderate-continuous exercise (all p > .13), aside from a reduced relative hypercapnic MCA slope at hours zero and one following moderate-continuous exercise (all p < .005). The current findings indicate the common inclusion criteria of a 12-24 hr time restriction on exercise can be reduced to two hours when performing CVR measures. Furthermore, the consistent nature of the CVR indices throughout the control day indicate reproducible testing sessions can be made between 8:00a.m. and 7:00p.m.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.