ArticleTransboundary and emerging diseases2020
Potential link of single nucleotide polymorphisms to virulence of vaccine-associated field strains of lumpy skin disease virus in South Africa.
Article in Transboundary and emerging diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- The global scenario of lumpy skin disease, its epidemiological investigation, and prevalence in livestock: A review.Veterinary and animal science · 2026Review
- Diagnostic approach, vaccination and treatment priorities for Lumpy Skin Disease in cattle: lessons from Balkan epidemics to Western Europe re-emergence (2025).Veterinary research communications · 2026Review
- Comparison of whole genome sequencing approaches for Capripox viruses.BMC genomics · 2026Article
- Genomic Analysis of Lumpy Skin Disease Virus from Western and Central Africa Suggests a Distinct Sub-Lineage Within the 1.2 LSDV Cluster.Pathogens (Basel, Switzerland) · 2025Article
- Genetic characterization of lumpy skin disease virus (LSDV) isolates from an outbreak on Great Nicobar Island, India, in 2022 reveals the involvement of a cluster 2.5 recombinant LSDV strain (East/Southeast Asian lineage).Archives of virology · 2025Article
- Monitoring of genetic alterations of lumpy skin disease virus in cattle after vaccination in Thailand.Journal of animal science and technology · 2025Article
- Article
- Detection and Genome Sequencing of Lumpy Skin Disease Viruses in Wildlife Game Species in South Africa.Viruses · 2024Article
- Complete Genomic Characterization of Lumpy Skin Disease Virus Isolates from Beef Cattle in Lopburi Province, Central Thailand, during 2021-2022.Veterinary sciences · 2023Article
- Dual analysis of wild-type and attenuatedmSphere · 2023Article
- Complete genome reconstruction of the global and European regional dispersal history of the lumpy skin disease virus.Journal of virology · 2023Article
- First complete genome sequence of lumpy skin disease virus directly from a clinical sample in South India.Virus genes · 2023Article
- Article
- Sign of APOBEC editing, purifying selection, frameshift, and in-frame nonsense mutations in the microevolution of lumpy skin disease virus.Frontiers in microbiology · 2023Article
- Lumpy skin disease: history, current understanding and research gaps in the context of recent geographic expansion.Frontiers in microbiology · 2023Review
- An in-depth bioinformatic analysis of the novel recombinant lumpy skin disease virus strains: from unique patterns to established lineage.BMC genomics · 2022Article
- A robust, cost-effective and widely applicable whole-genome sequencing protocol for capripoxviruses.Journal of virological methods · 2022Article
- Capripoxviruses, leporipoxviruses, and orthopoxviruses: Occurrences of recombination.Frontiers in microbiology · 2022Review
- Genetic Evidence of Multiple Introductions of Lumpy Skin Disease Virus into Saratov Region, Russia.Pathogens (Basel, Switzerland) · 2021Article
- Molecular Analysis of East African Lumpy Skin Disease Viruses Reveals a Mixed Isolate with Features of Both Vaccine and Field Isolates.Microorganisms · 2021Article
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Authors and funding
7 authors.
Funding
Abstract
South Africa is endemic for lumpy skin disease and is therefore reliant on various live attenuated vaccines for the control and prevention of the disease. In recent years, widespread outbreaks of vaccine-like strains of lumpy skin disease virus (LSDV) were reported internationally, leading to an increase in the generation of full genome sequences from field isolates. In this study, the complete genomes of six LSDVs submitted during active outbreaks in the 1990s in South Africa were generated. Based on phylogenetic analysis, the six viruses clustered with vaccine strains in LSDV Subgroup 1.1 and are subsequently referred to as vaccine-associated. The genetic differences between the phenotypically distinct vaccine and vaccine-associated strains were 67 single nucleotide polymorphisms (SNPs). This study characterized the location and possible importance of each of these SNPs in their role during virulence and host specificity.
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