Evidence map›Paper›PMID 32506639›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2021

Characterizing the landscape and impact of infections following kidney transplantation.

Kyle R Jackson, Jennifer D Motter, Sunjae Bae, Amber Kernodle, Jane J Long, William Werbel, Robin Avery, Christine Durand, Allan B Massie, Niraj Desai and 2 more

Open access · greenAbstract read
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 3 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 3 syntheses or guidelines pooled it, 59 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Infections After Kidney Transplantation From Donors With HIV to Recipients With HIV.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Observational
  10. Article
  11. Article
  12. Article
  13. Article
  14. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025
    Article
  15. Update on Hepatitis E Virus Infection 2025: Insights From an International Symposium.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Article
  16. Observational
  17. Article
  18. Primary care for recipients of kidney transplants.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025
    Article
  19. Longitudinal assessment of the effect of invasive fungal infections on transplant success in kidney transplant recipients.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Kyle R JacksonDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-8135-5377
Jennifer D MotterDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Sunjae BaeDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0003-0098-8816
Amber KernodleDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-6459-5280
Jane J LongDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
William WerbelDivision of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0003-2943-5895
Robin AveryDivision of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0001-7692-3619
Christine DurandDivision of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0003-2605-9257
Allan B MassieDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-5288-5125
Niraj DesaiDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Jacqueline Garonzik-WangDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Dorry L SegevDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0003-3205-1024
Johns Hopkins University · USNational Marrow Donor Program · US

Funding

RESEARCH TRAINING IN MICROBIAL DISEASEST32AI007291 · NIAID · JOHNS HOPKINS UNIVERSITY · PI JOEL N BLANKSON, Sara Elizabeth Cosgrove · 1986 to 2026
$9.1M
Patient Oriented Research in Kidney Disease and Transplant SurgeryK24DK101828 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI SEGEV, DORRY L. · 2014 to 2018
$922k
Determinants of chronic kidney disease in African-American live kidney donorsK01DK101677 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI MASSIE, ALLAN B · 2015 to 2019
$789k
Aggressive Center Report Cards to Safely Increase Transplantation of Suboptimal KidneysK23DK115908 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI GARONZIK WANG, JACQUELINE M · 2018 to 2021
$516k
The effect of socioeconomic status and environment characteristics on disparate postdonation health outcomes between Black and White living kidney donorsF32DK117563 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI KERNODLE, AMBER · 2018 to 2020
$240k
Differential Survival Benefit of Incompatible Living Donor Kidney Transplantation: Modeling Outcomes for Different Patient PhenotypesF32DK113719 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI JACKSON, KYLE R · 2017 to 2019
$238k
NIDDK NIH HHS F32 DK113719NIDDK NIH HHS F32DK113719NIDDK NIH HHS F32 DK117563NIDDK NIH HHS F32DK117563NIDDK NIH HHS K01 DK101677NIDDK NIH HHS K01DK101677NIDDK NIH HHS K23 DK115908NIDDK NIH HHS K23DK115908NIDDK NIH HHS K24 DK101828NIDDK NIH HHS K24DK101828
6 · The paper itself

Abstract

Infections remain a major threat to successful kidney transplantation (KT). To characterize the landscape and impact of post-KT infections in the modern era, we used United States Renal Data System (USRDS) data linked to the Scientific Registry of Transplant Recipients (SRTR) to study 141 661 Medicare-primary kidney transplant recipients from January 1, 1999 to December 31, 2014. Infection diagnoses were ascertained by International Classification of Diseases, Ninth Revision (ICD-9) codes. The cumulative incidence of a post-KT infection was 36.9% at 3 months, 53.7% at 1 year, and 78.0% at 5 years. The most common infections were urinary tract infection (UTI; 46.8%) and pneumonia (28.2%). Five-year mortality for kidney transplant recipients who developed an infection was 24.9% vs 7.9% for those who did not, and 5-year death-censored graft failure (DCGF) was 20.6% vs 10.1% (P < .001). This translated to a 2.22-fold higher mortality risk (adjusted hazard ratio [aHR]:

Indexed as

Kidney TransplantationAgedGraft RejectionHumansMedicareRisk FactorsTransplant RecipientsUnited States

Identifiers

PMID32506639
PMCPMC12404669
OpenAlexW3033673923

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.