Evidence map›Paper›PMID 32506485›Full record

ArticleInternational journal of cancer2020

Cell surface vimentin-positive circulating tumor cell-based relapse prediction in a long-term longitudinal study of postremission neuroblastoma patients.

Izhar S Batth, Long Dao, Arun Satelli, Abhisek Mitra, Sofia Yi, Hyangsoon Noh, Heming Li, Zachary Brownlee, Shouhao Zhou, Jeffrey Bond and 4 more

Erratum issuedAbstract read
In one paragraph

Article in International journal of cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Phytogalactolipids activate humoral immunity against colorectal cancer.Journal of experimental & clinical cancer research : CR · 2023
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Recent clinical research on the application of liquid biopsy in neuroblastoma.Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2022
    Review
  14. Extracellular Vimentin as a Target Against SARS-CoV-2 Host Cell Invasion.Small (Weinheim an der Bergstrasse, Germany) · 2022
    Article
  15. Article
  16. Extracellular vimentin as a target against SARS-CoV-2 host cell invasion.bioRxiv : the preprint server for biology · 2021
    Article
  17. Article
  18. Review
  19. Mechanical and Non-Mechanical Functions of Filamentous and Non-Filamentous Vimentin.BioEssays : news and reviews in molecular, cellular and developmental biology · 2020
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Izhar S BatthDepartment of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Long DaoDepartment of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.ORCID 0000-0002-7857-3242
Arun SatelliDepartment of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Abhisek MitraDepartment of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Sofia YiDepartment of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Hyangsoon NohDepartment of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Heming LiDepartment of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Zachary BrownleeDepartment of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Shouhao ZhouDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Jeffrey BondPediatric Oncology Translational Research Program, Helen DeVos Children's Hospital, Grand Rapids, Michigan, USA.
Jing WangDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Jonathan GillDepartment of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Giselle S ShollerPediatric Oncology Translational Research Program, Helen DeVos Children's Hospital, Grand Rapids, Michigan, USA.ORCID 0000-0002-2574-0203
Shulin LiDepartment of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

Funding

Develop CTC capture technology for both mesenchymal and non-mesenchymal tumorsR01EB026291 · NIBIB · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI LI, SHULIN · 2018 to 2021
$1.4M
NIBIB NIH HHS R01 EB026291NIH HHS R01EB026291 02
6 · The paper itself

Abstract

Neuroblastoma (NB) is a deadly childhood disease that carries a 50% chance of relapse for anyone in remission and similar level of 5-year survival. We investigated the value of our proprietary approach-cell surface vimentin (CSV) positive circulating tumor cells (CTC) to monitor treatment response and predict relapse in NB patients under remission in a Phase II long-term preventative clinical trial. We longitudinally analyzed peripheral blood samples from 93 patients for 27 cycles (~25 months) and discovered that the presence of CSV

Indexed as

Biomarkers, TumorCell Line, TumorClinical Trials, Phase II as TopicEarly Detection of CancerEflornithineEpithelial-Mesenchymal TransitionFemaleHumansLongitudinal StudiesMaleNeoplasm Recurrence, LocalNeoplastic Cells, CirculatingNeuroblastomaSensitivity and SpecificitySurvival AnalysisVimentinBiomarkers, TumorEflornithineVimentinVIM protein, humancirculating tumor celldifluoromethylornithineliquid biopsiesneuroblastomarelapse

Identifiers

PMID32506485
PMCPMC7839076

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.