Evidence map›Paper›PMID 32506281›Full record

ArticleThe European journal of health economics : HEPAC : health economics in prevention and care2020

An exploration of methods for obtaining 0 = dead anchors for latent scale EQ-5D-Y values.

Koonal K Shah, Juan Manuel Ramos-Goñi, Simone Kreimeier, Nancy J Devlin

Open access · hybridAbstract read
In one paragraph

Article in The European journal of health economics : HEPAC : health economics in prevention and care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 4 pooled it
11.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 4 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Review
  7. Article
  8. Nothing about us, without us? A reflection on and call for involving children in the process of valuing child health.The European journal of health economics : HEPAC : health economics in prevention and care · 2026
    Article
  9. Review
  10. Loss aversion in EQ-5D-Y-3L: does it explain differences in willingness to trade-off life years in adults and children?The European journal of health economics : HEPAC : health economics in prevention and care · 2025
    Article
  11. Valuing health-related quality of life: an EQ-5D-5L value set for Morocco.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  12. Article
  13. Comparing heuristic valuation processes between health state valuation from child and adult perspectives.The European journal of health economics : HEPAC : health economics in prevention and care · 2024
    Article
  14. Article
  15. The effect of duration and time preference on the gap between adult and child health state valuations in time trade-off.The European journal of health economics : HEPAC : health economics in prevention and care · 2024
    Article
  16. Understanding Canadian stakeholders' views on measuring and valuing health for children and adolescents: a qualitative study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Article
  17. Article
  18. Article
  19. Time and lexicographic preferences in the valuation of EQ-5D-Y with time trade-off methodology.The European journal of health economics : HEPAC : health economics in prevention and care · 2023
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 5 countries.

Koonal K ShahPHMR, London, UK. koonalshah@phmr.com.ORCID http://orcid.org/0000-0002-4927-7858
Juan Manuel Ramos-GoñiAxentiva Solutions, Tacoronte, Spain.
Simone KreimeierSchool of Public Health, Bielefeld University, Bielefeld, Germany.
Nancy J DevlinSchool of Health and Related Research, University of Sheffield, Sheffield, UK.
Bielefeld University · DEEuroQol Research Foundation · NLPublic Health England · GBThe University of Melbourne · AU

Funding

EuroQol Research Foundation 2016570
6 · The paper itself

Abstract

objectivesDiscrete choice experiments (DCEs) can be used to obtain latent scale values for the EQ-5D-Y, but these require anchoring at 0 = dead to meet the conventions of quality-adjusted life year (QALY) estimation. The primary aim of this study is to compare four preference elicitation methods for obtaining anchors for latent scale EQ-5D-Y values.

methodsFour methods were tested: visual analogue scale (VAS), DCE (with a duration attribute), lag-time time trade-off (TTO) and the location-of-dead (LOD) approach. In computer-assisted personal interviews, UK general public respondents valued EQ-5D-3L health states from an adult perspective and EQ-5D-Y health states from a 10-year-old child perspective. Respondents completed valuation tasks using all four methods, under both perspectives.

results349 interviews were conducted. Overall, respondents gave lower values under the adult perspective compared to the child perspective, with some variation across methods. The mean TTO value for the worst health state (33333) was about equal to dead in the child perspective and worse than dead in the adult perspective. The mean VAS rescaled value for 33333 was also higher in the child perspective. The DCE produced positive child perspective values and negative adult perspective values, though the models were not consistent. The LOD median rescaled value for 33333 was negative under both perspectives and higher in the child perspective. DISCUSSION: There was broad agreement across methods. Potential criteria for selecting a preferred anchoring method are presented. We conclude by discussing the decision-making circumstances under which utilities and QALY estimates for children and adults need to be commensurate to achieve allocative efficiency.

Indexed as

Decision Support TechniquesQuality-Adjusted Life YearsAdolescentAdultAgedChildCost-Benefit AnalysisFemaleHealth StatusHumansMaleMiddle AgedModels, EconomicPatient PreferenceUnited KingdomYoung AdultChildrenEQ-5D-YQuality-adjusted life yearStated preferencesValuation

Identifiers

PMID32506281
PMCPMC7423806
OpenAlexW3033294826

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.