ArticleJournal of cancer survivorship : research and practice2020
Looking under the hood of "the Cadillac of cancers:" radioactive iodine-related craniofacial side effects among patients with thyroid cancer.
Article in Journal of cancer survivorship : research and practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Health-Related Quality of Life following Total Thyroidectomy and Lobectomy for Differentiated Thyroid Carcinoma: A Systematic Review.Current oncology (Toronto, Ont.) · 2022Pooled it
- Association of radioactive iodine treatment with survivorship symptoms and primary care utilisation in women of reproductive age with thyroid cancer: a retrospective cohort study.Family medicine and community health · 2026Article
- Evaluation of Dry Eye Parameters in Patients with Papillary Thyroid Carcinoma.Journal of clinical medicine · 2026Article
- Patient and Provider Perspectives of a Web-Based Intervention to Support Symptom Management After Radioactive Iodine Treatment for Differentiated Thyroid Cancer: Qualitative Study.JMIR formative research · 2025Article
- Review
- "No such thing as good cancer": a qualitative exploration of the experience of early-onset thyroid cancer in survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Salivary, lacrimal and nasal (SALANS) measure to assess side effects following radioactive iodine treatment: development, psychometric properties, and factor structure.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- [The lacrimal apparatus as an organ at risk during radionuclide therapy].Problemy endokrinologii · 2024Article
- Hearing the Voices of Australian Thyroid Cancer Survivors: Qualitative Thematic Analysis of Semistructured Interviews Identifies Unmet Support Needs.Thyroid : official journal of the American Thyroid Association · 2023Article
- Social Determinants of Health and Quality of Life in Endocrine Surgery Patients.The Journal of surgical research · 2023Article
- Probiotic Bacteria Cannot Mitigate the Adverse Effects of Radioactive Iodine-131 Treatment.Cancers · 2023Article
- Impact of Nasolacrimal Dysfunction in Thyroid Cancer Survivors.Thyroid : official journal of the American Thyroid Association · 2022Article
- Radioactive Iodine Symptom Burden, Psychosocial Factors, and Health-related Quality of Life among Differentiated Thyroid Cancer Survivors: A Cross-Sectional Analysis.Journal of psychosocial oncology research and practiceArticle
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
purposeDespite having a generally favorable prognosis, differentiated thyroid cancer is known to have a significant, long-term impact on the quality of life of survivors. We wished to investigate short- and long-term effects among thyroid cancer survivors following radioactive iodine therapy.
methodsWe conducted eight focus groups (N = 47) to understand patients' experiences of short- and long-term effects after radioactive iodine treatment and the impact these treatment-related side effects had on patients' quality of life. We elicited responses regarding experiences with side effects following radioactive iodine treatment, particularly salivary, lacrimal, and nasal symptoms. We transcribed audiotapes and conducted qualitative analyses to identify codes and themes.
resultsWe identified eight broad themes from the qualitative analyses. Themes reflecting physical symptoms included dry mouth, salivary gland dysfunction, altered taste, eye symptoms such as tearing or dryness, and epistaxis. Psychosocial themes included lack of knowledge and preparation for treatment, regret of treatment, and distress that thyroid cancer is labeled as a "good cancer."
conclusionsThyroid cancer survivors reported a wide range of radioactive iodine treatment-related effects and psychosocial concerns that appear to reduce quality of life. The psychosocial concerns reported by participants underscore the significant unmet information and support needs prior to and following RAI treatment among individuals diagnosed with thyroid cancer. IMPLICATIONS FOR CANCER SURVIVORS: Future research is needed to help both patients and physicians understand the effect of radioactive iodine on quality of life, and to better assess the benefits versus the risks of radioactive iodine therapy.
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