Evidence map›Paper›PMID 32506180›Full record

ArticleBiological trace element research2021

Caffeic Acid Protects against Iron-Induced Cardiotoxicity by Suppressing Angiotensin-Converting Enzyme Activity and Modulating Lipid Spectrum, Gluconeogenesis and Nucleotide Hydrolyzing Enzyme Activities.

Veronica F Salau, Ochuko L Erukainure, Md Shahidul Islam

Abstract read
PubMed Publisher
In one paragraph

Article in Biological trace element research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
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  6. Article
  7. Article
  8. Review
  9. Effect of Flavonoid-Rich Extract FromBioinformatics and biology insights · 2022
    Article
  10. Review
  11. Frontiers in pharmacology · 2021
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Veronica F SalauDepartment of Biochemistry, School of Life Sciences, University of KwaZulu-Natal, Westville Campus, Durban, 4000, South Africa.
Ochuko L ErukainureDepartment of Biochemistry, School of Life Sciences, University of KwaZulu-Natal, Westville Campus, Durban, 4000, South Africa.
Md Shahidul IslamDepartment of Biochemistry, School of Life Sciences, University of KwaZulu-Natal, Westville Campus, Durban, 4000, South Africa. islamd@ukzn.ac.za.ORCID http://orcid.org/0000-0003-0309-9491
University of KwaZulu-Natal · ZAUniversity of the Free State · ZAVeritas University · NG

Funding

Inyuvesi Yakwazulu-Natali 218087036National Department of Health (ZA) Grant Support for Women and Young Researchers
6 · The paper itself

Abstract

The protective effects of caffeic acid on angiotensin-converting enzyme (ACE) and purinergic enzyme activities, as well as gluconeogenesis was investigated in iron-induced cardiotoxicity. Cardiotoxicity was induced in heart tissues harvested from healthy male SD rats by 0.1 mM FeSO

Indexed as

CardiotoxicityIronAngiotensinsAnimalsAntioxidantsCaffeic AcidsGluconeogenesisLipidsMaleNucleotidesOxidative StressRatsRats, Sprague-DawleyAngiotensinsAntioxidantscaffeic acidCaffeic AcidsIronLipidsNucleotidesCaffeic acidCardio-metabolismIron cardiotoxicityPurinergic activity

Identifiers

PMID32506180
OpenAlexW3033742473

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.