Evidence map›Paper›PMID 32506123›Full record

ArticleNeuro-oncology2020

Baseline requirements for novel agents being considered for phase II/III brain cancer efficacy trials: conclusions from the Adult Brain Tumor Consortium's first workshop on CNS drug delivery.

Stuart A Grossman, Carlos G Romo, Michelle A Rudek, Jeffrey Supko, Joy Fisher, L Burt Nabors, Patrick Y Wen, David M Peereboom, Benjamin M Ellingson, William Elmquist and 6 more

Abstract read
In one paragraph

Article in Neuro-oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Review
  4. Article
  5. Review
  6. Focused ultrasound for brain metastases.Neuro-oncology advances · 2026
    Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Impact of Frontline Ivosidenib on Volumetric Growth Patterns in Isocitrate Dehydrogenase-mutant Astrocytic and Oligodendroglial Tumors.Clinical cancer research : an official journal of the American Association for Cancer Research · 2023
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. LargerEJNMMI research · 2022
    Article
  19. Glioblastoma Clinical Trials: Current Landscape and Opportunities for Improvement.Clinical cancer research : an official journal of the American Association for Cancer Research · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Stuart A GrossmanJohns Hopkins University, Baltimore, Maryland.
Carlos G RomoJohns Hopkins University, Baltimore, Maryland.
Michelle A RudekJohns Hopkins University, Baltimore, Maryland.
Jeffrey SupkoMassachusetts General Hospital, Boston, Massachusetts.
Joy FisherJohns Hopkins University, Baltimore, Maryland.
L Burt NaborsUniversity of Alabama Birmingham, Birmingham, Alabama.
Patrick Y WenDana-Farber Cancer Institute, Boston, Massachusetts.
David M PeereboomCleveland Clinic, Cleveland, Ohio.
Benjamin M EllingsonUniversity of California Los Angeles, Los Angeles, California.
William ElmquistUniversity of Minnesota, Minneapolis, Minnesota.
Fred G BarkerMassachusetts General Hospital, Boston, Massachusetts.
David KamsonJohns Hopkins University, Baltimore, Maryland.
Jann N SarkariaMayo Clinic, Rochester, Minnesota.
William TimmerNational Cancer Institute, Bethesda, Maryland.
Ranjit S BindraYale University, New Haven, Connecticut.
Xiaobu YeJohns Hopkins University, Baltimore, Maryland.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
UCLA SPORE in Brain CancerP50CA211015 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Yvonne Yu-Hsuan Chen · 2017 to 2026
$25.2M
Adult Brain Tumor Consortium (ABTC)UM1CA137443 · NCI · JOHNS HOPKINS UNIVERSITY · PI GROSSMAN, STUART A · 2014 to 2020
$9.7M
NCATS NIH HHS UL1 TR001863NCI NIH HHS P50 CA211015NCI NIH HHS UM1 CA137443
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Brain NeoplasmsPharmaceutical PreparationsAdultClinical Trials, Phase II as TopicClinical Trials, Phase III as TopicDrug Delivery SystemsHumansPharmaceutical Preparations

Identifiers

PMID32506123
PMCPMC7566550

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.