Evidence map›Paper›PMID 32505783›Full record

ArticleCell calcium2020

GCaMP as an indirect measure of electrical activity in rat trigeminal ganglion neurons.

Jane E Hartung, Michael S Gold

Abstract read
In one paragraph

Article in Cell calcium, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
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  5. Article
  6. Mesoscopic mapping of hemodynamic responses and neuronal activity during pharmacologically induced interictal spikes in awake and anesthetized mice.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
  7. Article
  8. Sex differences in zymosan-induced behavioral visceral hypersensitivity and colorectal afferent sensitization.American journal of physiology. Gastrointestinal and liver physiology · 2024
    Article
  9. Article
  10. Article
  11. Ionizing radiation alters functional neurotransmission inFrontiers in cellular neuroscience · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jane E HartungDepartment of Neurobiology and the Pittsburgh Center for Pain Research, University of Pittsburgh, United States. Electronic address: jeh206@pitt.edu.
Michael S GoldDepartment of Neurobiology and the Pittsburgh Center for Pain Research, University of Pittsburgh, United States. Electronic address: msg22@pitt.edu.

Funding

Training in Mechanisms and Clinical Presentation of PainT32NS073548 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Jami Lynn Saloman, BRADLEY K. TAYLOR · 2012 to 2026
$3.1M
Peripheral GABAA Receptor SignalingR01DK107966 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GOLD, MICHAEL S · 2016 to 2020
$1.9M
Mechanisms of MigraineR01NS083347 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GOLD, MICHAEL S · 2014 to 2018
$1.8M
Inflammation-induced changes in spinal GABA-A receptor signalingR01NS063010 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GOLD, MICHAEL S · 2009 to 2011
$1.1M
Traumatic Brain Injury, Stress, and HeadacheF32NS103231 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HARTUNG, JANE E. · 2017 to 2018
$115k
NIDDK NIH HHS R01 DK107966NINDS NIH HHS F32 NS103231NINDS NIH HHS R01 NS063010NINDS NIH HHS R01 NS083347NINDS NIH HHS T32 NS073548
6 · The paper itself

Abstract

While debate continues over whether somatosensory information is transmitted via labeled line, population coding, frequency coding, or some combination therein, researchers have begun to address this question at the level of the primary afferent by using optical approaches that enable the assessment of neural activity in hundreds to even thousands of neurons simultaneously. However, with limited availability of tools to optically assess electrical activity in large populations of neurons, researchers have turned to genetically encoded Ca

Indexed as

ElectricityAction PotentialsAnimalsCalciumCalcium-Binding ProteinsDependovirusFluorescenceIntracellular SpaceMaleNeuronsProtein IsoformsRats, Sprague-DawleyTrigeminal GanglionCalciumCalcium-Binding ProteinsProtein IsoformsCa(2+)imagingIntracellular calciumPrimary afferentSensory neuronsSomatosensory coding

Identifiers

PMID32505783
PMCPMC7331800

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.