SynthesisAcademic radiology2020
CT Manifestations and Clinical Characteristics of 1115 Patients with Coronavirus Disease 2019 (COVID-19): A Systematic Review and Meta-analysis.
Synthesis in Academic radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04407468 (Awake Prone Positioning and Oxygen Therapy in Patients With COVID-19), which is not on this map. Cited by 34 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Awake Prone Positioning and Oxygen Therapy in Patients With COVID-19 (APRONOX)
Who cites it
34 citing papers in PubMed, 5 syntheses or guidelines pooled it, 83 citations in OpenAlex.
- The difference of variation types between late-onset multiple acyl-CoA dehydrogenase deficiency patients carrying biallelic and single heterozygous variations in ETFDH: a systematic review and meta-analysis.Orphanet journal of rare diseases · 2025Pooled it
- Prevalence, Features and Degree of Association of Oral Lesions in COVID-19: A Systematic Review of Systematic Reviews.International journal of environmental research and public health · 2022Pooled it
- Clinical Features of COVID-19 Patients in the First Year of Pandemic: A Systematic Review and Meta-Analysis.Biological research for nursing · 2022Pooled it
- Chest CT abnormalities in COVID-19: a systematic review.International journal of medical sciences · 2021Pooled it
- Pediatric lung imaging features of COVID-19: A systematic review and meta-analysis.Pediatric pulmonology · 2021Pooled it
- Artificial intelligence-powered chest computed tomography analysis unveils prognostic insights for COVID-19 mortality among prevalent hemodialysis patients.Kidney research and clinical practice · 2026Article
- Factors of progression to severity and death in COVID-19 patients at two health care sites in Bamako, Mali.BMC infectious diseases · 2025Article
- Early predictors of intensive care unit admission among COVID-19 patients in Qatar.Frontiers in public health · 2024Article
- Digital tomosynthesis improves chest radiograph accuracy and reduces microbiological false negatives in COVID-19 diagnosis.Emergency radiology · 2023Article
- The Threat of Adversarial Attack on a COVID-19 CT Image-Based Deep Learning System.Bioengineering (Basel, Switzerland) · 2023Article
- Rapid artificial intelligence solutions in a pandemic-The COVID-19-20 Lung CT Lesion Segmentation Challenge.Medical image analysis · 2022Article
- Evaluation of chest CT-scan appearances of COVID-19 according to RSNA classification system.Journal of family medicine and primary care · 2022Article
- Rapid 8-Zone Lung Ultrasound Protocol is Comparable to a Full 12-Zone Protocol for Outcome Prediction in Hospitalized COVID-19 Patients.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2022Article
- Molecular and serology methods in the diagnosis of COVID-19: An overview.World journal of methodology · 2022Review
- Clinical indicators, nursing diagnoses, and mortality risk in critically ill patients with COVID-19: a retrospective cohort.Revista da Escola de Enfermagem da U S P · 2022Article
- Molecular and Physiological Aspects of SARS-CoV-2 Infection in Women and Pregnancy.Frontiers in global women's health · 2022Review
- COVID19 biomarkers: What did we learn from systematic reviews?Frontiers in cellular and infection microbiology · 2022Review
- Correlation Between Low-Dose Chest Computed Tomography and RT-PCR Results for the Diagnosis of COVID-19: A Report of 27,824 Cases in Tehran, Iran.Academic radiology · 2021Article
- Lung ultrasound in predicting COVID-19 clinical outcomes: A prospective observational study.Journal of the American College of Emergency Physicians open · 2021Article
- Computerized tomography of the Thorax for surgical patients during the COVID-19 pandemic: Was it useful?International journal of clinical practice · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
RATIONALE AND
objectivesWe aimed to assess the prevalence of significant computed tomographic(CT) manifestations and describe some notable features based on chest CT images, as well as the main clinical features of patients with coronavirus disease 2019(COVID-19). MATERIALS AND
methodsA systematic literature search of PubMed, EMBASE, the Cochrane Library, and Web of Science was performed to identify studies assessing CT features, clinical, and laboratory results of COVID-19 patients. A single-arm meta-analysis was conducted to obtain the pooled prevalence and 95% confidence interval (95% CI).
resultsA total of 14 articles (including 1115 patients) based on chest CT images were retrieved. In the lesion patterns on chest CTs, we found that pure ground-glass opacities (GGO) (69%, 95% CI 58-80%), consolidation (47%, 35-60%) and "air bronchogram sign" (46%, 25-66%) were more common than the atypical lesion of "crazy-paving pattern" (15%, 8-22%). With regard to disease extent and involvement, 70% (95% CI 46-95%) of cases showed a location preference for the right lower lobe, 65% (58-73%) of patients presented with ≥3 lobes involvement, and meanwhile, 42% (32-53%) of patients had involvement of all five lobes, while 67% (55-78%) of patients showed a predominant peripheral distribution. An understanding of some important CT features might be helpful for medical surveillance and management. In terms of clinical features, muscle soreness (21%, 95% CI 15-26%) and diarrhea (7%, 4-10%) were minor symptoms compared to fever (80%, 74-87%) and cough (53%, 33-72%).
conclusionChest CT manifestations in patients with COVID-19, as well as its main clinical characteristics, might be helpful in disease evolution and management.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.