Evidence map›Paper›PMID 32505525›Full record

ArticleJournal of cystic fibrosis : official journal of the European Cystic Fibrosis Society2021

Pseudomonas aeruginosa antimicrobial susceptibility test (AST) results and pulmonary exacerbation treatment responses in cystic fibrosis.

Donald R VanDevanter, Sonya L Heltshe, Jay B Hilliard, Michael W Konstan

Open access · greenAbstract read
In one paragraph

Article in Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Donald R VanDevanterDepartment of Pediatrics, Case Western Reserve University School of Medicine, Cleveland OH, USA. Electronic address: drv15@case.edu.
Sonya L HeltsheCFF Therapeutics Development Network Coordinating Center, Seattle Children's Research Institute, Seattle, WA and Department of Pediatrics, University of Washington School of Medicine, Seattle, WA, USA.
Jay B HilliardDepartment of Pediatrics, Case Western Reserve University School of Medicine, Cleveland OH, USA; Department of Pediatrics, Rainbow Babies and Children's Hospital, Cleveland OH, USA.
Michael W KonstanDepartment of Pediatrics, Case Western Reserve University School of Medicine, Cleveland OH, USA; Department of Pediatrics, Rainbow Babies and Children's Hospital, Cleveland OH, USA.
Rainbow Babies & Children's Hospital · USCase Western Reserve University · USSeattle Children's Hospital · US

Funding

Clinical and Translational Science Collaborative of ClevelandUL1TR002548 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI MCCOMSEY, GRACE A · 2018 to 2022
$35.5M
Translational Research in Cystic FibrosisP30DK027651 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI DRUMM, MITCHELL L · 1986 to 2014
$15.6M
NCATS NIH HHS UL1 TR002548NIDDK NIH HHS P30 DK027651
6 · The paper itself

Abstract

Background Antimicrobial susceptibility testing (AST) of bacterial isolates is a time- and resource-intensive procedure recommended by cystic fibrosis (CF) treatment guidelines for antimicrobial selection for pulmonary exacerbation (PEx) treatment. Methods We studied relationships between Pseudomonas aeruginosa (Pa) isolate AST results, antipseudomonal PEx treatments, and treatment responses as change in weight and percent predicted forced expiratory volume in 1 s (ppFEV

Indexed as

AdolescentAdultAnti-Bacterial AgentsCystic FibrosisFemaleHumansMaleMicrobial Sensitivity TestsPseudomonas aeruginosaPseudomonas InfectionsRespiratory Function TestsSymptom Flare UpAnti-Bacterial AgentsCystic fibrosisPseudomonas aeruginosaPulmonary exacerbationSusceptibility testing

Identifiers

PMID32505525
PMCPMC7714709
OpenAlexW3034054467

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.