Evidence map›Paper›PMID 32505113›Full record

ArticleJournal of chromatography. B, Analytical technologies in the biomedical and life sciences2020

Purification of Lumbricus terrestris erythrocruorin (LtEc) with anion exchange chromatography.

Brandon Timm, Osheiza Abdulmalik, Atis Chakrabarti, Jacob Elmer

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Purification ofACS biomaterials science & engineering · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Brandon TimmDepartment of Chemical and Biological Engineering, Villanova University, 800 East Lancaster Avenue, Villanova, PA 19085, USA.
Osheiza AbdulmalikDiv. of Hematology, Abramson Building, The Children's Hospital of Philadelphia, 34th St. and Civic Center Blvd, Philadelphia, PA 19104, USA.
Atis ChakrabartiTosoh Bioscience, LLC, 3604 Horizon Drive, King of Prussia, PA 19406, USA.
Jacob ElmerDepartment of Chemical and Biological Engineering, Villanova University, 800 East Lancaster Avenue, Villanova, PA 19085, USA. Electronic address: jacob.elmer@villanova.edu.
Villanova University · USChildren's Hospital of Philadelphia · US

Funding

Evaluation of Invertebrate Hemoglobins as Effective, Safe, and Ultra-Stable Blood SubstitutesR15HL133880 · NHLBI · VILLANOVA UNIVERSITY · PI ELMER, JACOB JAMES · 2017 to 2017
$432k
NHLBI NIH HHS R15 HL133880
6 · The paper itself

Abstract

The naturally extracellular hemoglobin (erythrocruorin) of the Canadian nightcrawler, Lumbricus terrestris (LtEc), is a unique oxygen transport protein that may be an effective substitute for donated human blood. Indeed, this ultra-high molecular weight (~3.6 MDa) hemoglobin has already been shown to avoid the side effects associated with previous hemoglobin-based oxygen carriers and its high thermal stability (T

Indexed as

HemoglobinsAnimalsBlood SubstitutesChromatography, AffinityChromatography, Ion ExchangeComplex MixturesEndotoxinsOligochaetaOxygenBlood SubstitutesComplex MixturesEndotoxinserythrocruorinHemoglobinsOxygenAnion exchange chromatographyBlood substituteErythrocruorinHemoglobinImmobilized metal ion affinity chromatographyProtein purification

Identifiers

PMID32505113
PMCPMC7346680
OpenAlexW3025981573

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.