Evidence map›Paper›PMID 32505069›Full record

ReviewMedical hypotheses2020

Hydrogen peroxide and viral infections: A literature review with research hypothesis definition in relation to the current covid-19 pandemic.

Arturo Armone Caruso, Antonio Del Prete, Antonio Ivan Lazzarino

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Medical hypotheses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04721457 (Mouth Rinses Efficacy on Salivary SARS-CoV-2 Viral Load), which is not on this map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04721457 phase4completednot on this mapstarted 2021, after this paper: background citation

Mouth Rinses Efficacy on Salivary SARS-CoV-2 Viral Load: A Randomized Clinical Trial

TypeinterventionalSponsorKing Abdulaziz UniversityRan2021 to 2021Enrolled90ConditionsSARS-CoV-2, COVID-19, Mouthwashes, Viral LoadArmsDistilled Water, 1% Povidone Iodine (PVP-I), 1.5% Hydrogen Peroxide (H2O2), 0.075% Cetylpyridinium Chloride (CPC), 0.1% Sodium Hypochlorite
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

  1. Pooled it
  2. Effect of 1% HInternational dental journal · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Arturo Armone CarusoDepartment of Otolaryngology, AIAS di Afragola, Naples, Italy.
Antonio Del PreteDepartment of Ophthalmology, Università degli studi di Napoli Federico II, Naples, Italy.
Antonio Ivan LazzarinoEPISTATA - Agency for Clinical Research and Medical Statistics, London, United Kingdom. Electronic address: a.lazzarino@ucl.ac.uk.
AIAS Bologna · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We reviewed the literature concerning the innate response from nasal and oral epithelial cells and their reaction to hydrogen peroxide (H

Indexed as

COVID-19 Drug TreatmentCOVID-19Epithelial CellsHumansHydrogen PeroxideImmunity, InnateIn Vitro TechniquesModels, ImmunologicalMouthwashesNasal SpraysPandemicsSARS-CoV-2Virus DiseasesHydrogen PeroxideMouthwashesNasal SpraysCoronavirusCOVID-19Hydrogen peroxideInnate immunitySARS-CoV-2Viruses

Identifiers

PMID32505069
PMCPMC7262503
OpenAlexW3031752521

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.