Evidence map›Paper›PMID 32504817›Full record

ArticleNeuroImage2020

DeepDTI: High-fidelity six-direction diffusion tensor imaging using deep learning.

Qiyuan Tian, Berkin Bilgic, Qiuyun Fan, Congyu Liao, Chanon Ngamsombat, Yuxin Hu, Thomas Witzel, Kawin Setsompop, Jonathan R Polimeni, Susie Y Huang

Abstract read
In one paragraph

Article in NeuroImage, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed.

  1. Article
  2. Article
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  5. Image Distortion Correction for Diffusion MR Imaging Using a Transformer-based U-Net.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Discovery of Abundant Nano-scale Lymphatic-like Vessels in Brains.bioRxiv : the preprint server for biology · 2026
    Article
  10. Article
  11. Synthetic X-Q space learning for diffusion MRI parameter estimation: a pilot study in breast DKI.International journal of computer assisted radiology and surgery · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Qiyuan TianAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, United States; Harvard Medical School, Boston, MA, United States. Electronic address: qtian@mgh.harvard.edu.
Berkin BilgicAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, United States; Harvard Medical School, Boston, MA, United States; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, United States.
Qiuyun FanAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, United States; Harvard Medical School, Boston, MA, United States.
Congyu LiaoAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, United States; Harvard Medical School, Boston, MA, United States.
Chanon NgamsombatAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, United States; Department of Radiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Thailand.
Yuxin HuDepartment of Electrical Engineering, Stanford University, Stanford, CA, United States.
Thomas WitzelAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, United States; Harvard Medical School, Boston, MA, United States.
Kawin SetsompopAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, United States; Harvard Medical School, Boston, MA, United States; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, United States.
Jonathan R PolimeniAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, United States; Harvard Medical School, Boston, MA, United States; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, United States.
Susie Y HuangAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, United States; Harvard Medical School, Boston, MA, United States; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, United States.

Funding

Mapping the Human Connectome: Structure, Function, and HeritabilityU54MH091657 · NIMH · WASHINGTON UNIVERSITY · PI UGURBIL, KAMIL, VAN ESSEN, DAVID C · 2010 to 2014
$34.7M
CONNECTOME 2.0: DEVELOPING THE NEXT GENERATION HUMAN MRI SCANNER FOR BRIDGING STUDIES OF THE MICRO-, MESO- AND MACRO-CONNECTOMEU01EB026996 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI BASSER, PETER J., HUANG, SUSIE YI · 2018 to 2022
$14.2M
Training and Dissemination CoreP41EB030006 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI BRUCE R ROSEN · 2020 to 2026
$10.9M
Project 4P41EB015896 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI ROSEN, BRUCE R · 2012 to 2018
$9.8M
FreeSurfer Development, Maintenance, and HardeningR01EB023281 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Bruce Fischl, Douglas Nowlin Greve · 2016 to 2026
$5.6M
Improving Human fMRI through Modeling and Imaging Microvascular Dynamics: Administrative SupplementR01MH111419 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI POLIMENI, JONATHAN RIZZO · 2016 to 2020
$4.9M
MRI technology for restoring brain image quality for pediatric patients with metallic orthodontic hardwareR01EB028797 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Berkin Bilgic, Jason P Stockmann · 2020 to 2026
$3.0M
Characterizing axonal damage in multiple sclerosis using TractCaliber MRIK23NS096056 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI HUANG, SUSIE YI · 2016 to 2020
$877k
NIBIB NIH HHS P41 EB015896NIBIB NIH HHS P41 EB030006NIBIB NIH HHS R01 EB023281NIBIB NIH HHS R01 EB028797NIBIB NIH HHS U01 EB026996NIMH NIH HHS R01 MH111419NIMH NIH HHS U54 MH091657NINDS NIH HHS K23 NS096056
6 · The paper itself

Abstract

Diffusion tensor magnetic resonance imaging (DTI) is unsurpassed in its ability to map tissue microstructure and structural connectivity in the living human brain. Nonetheless, the angular sampling requirement for DTI leads to long scan times and poses a critical barrier to performing high-quality DTI in routine clinical practice and large-scale research studies. In this work we present a new processing framework for DTI entitled DeepDTI that minimizes the data requirement of DTI to six diffusion-weighted images (DWIs) required by conventional voxel-wise fitting methods for deriving the six unique unknowns in a diffusion tensor using data-driven supervised deep learning. DeepDTI maps the input non-diffusion-weighted (b ​= ​0) image and six DWI volumes sampled along optimized diffusion-encoding directions, along with T

Indexed as

ConnectomeDeep LearningNeural Networks, ComputerBrainDiffusion Tensor ImagingHumansImage Processing, Computer-AssistedNerve NetConvolutional neural networkData redundancyDeep learningDenoisingDiffusion tensor imagingDiffusion tractographyResidual learningTract-specific analysis

Identifiers

PMID32504817
PMCPMC7646449

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.