Evidence map›Paper›PMID 32504331›Full record

SynthesisInternational journal of colorectal disease2020

Sigmoid resection with primary anastomosis versus the Hartmann's procedure for perforated diverticulitis with purulent or fecal peritonitis: a systematic review and meta-analysis.

Daniël Pv Lambrichts, Pim P Edomskis, Ruben D van der Bogt, Gert-Jan Kleinrensink, Willem A Bemelman, Johan F Lange

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in International journal of colorectal disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Contemporary management of diverticulitis.Surgery open science · 2024
    Article
  13. Observational
  14. Article
  15. Review
  16. Review
  17. Article
  18. State-of-the-art surgery for sigmoid diverticulitis.Langenbeck's archives of surgery · 2022
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Daniël Pv LambrichtsDepartment of Surgery, Erasmus University Medical Center, Rotterdam, 3015 GD, The Netherlands. d.lambrichts@erasmusmc.nl.ORCID https://orcid.org/0000-0002-4602-3115
Pim P EdomskisDepartment of Surgery, Erasmus University Medical Center, Rotterdam, 3015 GD, The Netherlands.ORCID https://orcid.org/0000-0001-8995-4166
Ruben D van der BogtDepartment of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0002-7341-9975
Gert-Jan KleinrensinkDepartment of Neuroscience, Erasmus University Medical Center, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0002-9073-3181
Willem A BemelmanDepartment of Surgery, Amsterdam University Medical Center, AMC, Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0002-1037-9945
Johan F LangeDepartment of Surgery, Erasmus University Medical Center, Rotterdam, 3015 GD, The Netherlands.
Erasmus MC · NLAmsterdam University Medical Centers · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe optimal surgical approach for perforated diverticulitis with purulent or fecal peritonitis (Hinchey grade III or IV) remains debated. In recent years, accumulating evidence comparing sigmoid resection with primary anastomosis (PA) with the Hartmann's procedure (HP) was presented. Therefore, the aim was to provide an updated and extensive synthesis of the available evidence.

methodsA systematic search in Embase, MEDLINE, Cochrane, and Web of Science databases was performed. Studies comparing PA to HP for adult patients with Hinchey III or IV diverticulitis were included. Data on mortality, morbidity, stoma reversal, and patient-reported and cost-related outcomes were extracted. Random effects models were used to pool data and estimate odds ratios (ORs).

resultsFrom a total of 1560 articles, four randomized controlled trials and ten observational studies were identified, reporting on 1066 Hinchey III/IV patients. Based on trial outcomes, PA was found to be favorable over HP in terms of stoma reversal rates (OR 2.62, 95% CI 1.29, 5.31) and reversal-related morbidity (OR 0.33, 95% CI 0.16, 0.69). No differences in mortality (OR 0.83, 95% CI 0.32, 2.19), morbidity (OR 0.99, 95% CI 0.65, 1.51), and reintervention rates (OR 0.90, 95% CI 0.39, 2.11) after the index procedure were demonstrated. Data on patient-reported and cost-related outcomes were scarce, as well as outcomes in PA patients with or without ileostomy construction and Hinchey IV patients.

conclusionAlthough between-study heterogeneity needs to be taken into account, the present results indicate that primary anastomosis seems to be the preferred option over Hartmann's procedure in selected patients with Hinchey III or IV diverticulitis.

Indexed as

DiverticulitisDiverticulitis, ColonicIntestinal PerforationPeritonitisAdultAnastomosis, SurgicalColon, SigmoidColostomyHumansTreatment OutcomeHartmann’s procedurePerforated diverticulitisPeritonitisPrimary anastomosis

Identifiers

PMID32504331
PMCPMC7340681
OpenAlexW3033359134

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.