Evidence map›Paper›PMID 32504291›Full record

SynthesisQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2020

Health-related quality of life overview after different curative treatment options in muscle-invasive bladder cancer: an umbrella review.

Elke Rammant, Lisa Van Wilder, Mieke Van Hemelrijck, Nele S Pauwels, Karel Decaestecker, Charles Van Praet, Renée Bultijnck, Piet Ost, Thomas Van Vaerenbergh, Sofie Verhaeghe and 2 more

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 4 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 4 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. The current use of the EORTC QLQ-NMIBC24 and QLQ-BLM30 questionnaires for the assessment of health-related quality of life in bladder cancer patients: a systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
    Pooled it
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  14. Radical cystectomy and urinary diversion in women.Translational andrology and urology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Elke RammantDepartment of Human Structure and Repair, Ghent University, Corneel Heymanslaan 10, 9000, Ghent, Belgium. elke.rammant@ugent.be.ORCID http://orcid.org/0000-0001-6130-2502
Lisa Van WilderDepartment of Public Health and Primary Care, University Hospital, Ghent University, Ghent, Belgium.
Mieke Van HemelrijckSchool of Cancer and Pharmaceutical Studies, Translational Oncology & Urology Research (TOUR), King's College London, London, UK.
Nele S PauwelsThe Knowledge Center for Health Ghent, Ghent University, Ghent, Belgium.
Karel DecaesteckerDepartment of Urology, Ghent University Hospital, Ghent, Belgium.
Charles Van PraetDepartment of Urology, Ghent University Hospital, Ghent, Belgium.
Renée BultijnckDepartment of Human Structure and Repair, Ghent University, Corneel Heymanslaan 10, 9000, Ghent, Belgium.
Piet OstDepartment of Human Structure and Repair, Ghent University, Corneel Heymanslaan 10, 9000, Ghent, Belgium.
Thomas Van VaerenberghDepartment of Human Structure and Repair, Ghent University, Corneel Heymanslaan 10, 9000, Ghent, Belgium.
Sofie VerhaegheDepartment of Public Health and Primary Care, University Centre for Nursing and Midwifery, Ghent University, Ghent, Belgium.
Ann Van HeckeDepartment of Public Health and Primary Care, University Centre for Nursing and Midwifery, Ghent University, Ghent, Belgium.
Valérie FonteyneDepartment of Radiation Oncology, Ghent University Hospital, Ghent, Belgium.
Ghent University Hospital · BEGhent University · BEKing's College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis umbrella review aims to evaluate the quality, summarize and compare the conclusions of systematic reviews investigating the impact of curative treatment options on health-related quality of life (HRQoL) in muscle-invasive bladder cancer (MIBC).

methodsThe Cochrane Library, MEDLINE, Embase and Web of Science were searched independently by two authors from inception until 06 January 2020. Systematic reviews and meta-analyses assessing the impact of any curative treatment option on HRQol in MIBC patients were eligible. Risk of bias was assessed using the AMSTAR 2 tool.

resultsThirty-two reviews were included. Robot-assisted RC with extracorporeal urinary diversion and open RC have similar HRQoL (n = 10). Evidence for pelvic organ-sparing RC was too limited (n = 2). Patients with a neobladder showed better overall and physical HRQoL outcomes, but worse urinary function in comparison with ileal conduit (n = 17). Bladder-preserving radiochemotherapy showed slightly better urinary and sexual but worse gastro-intestinal HRQoL outcomes in comparison with RC patients (n = 6). Quality of the reviews was low in more than 50% of the available reviews and most of the studies included in the reviews were nonrandomized studies.

conclusionThis umbrella review gives a comprehensive overview of the available evidence to date.

Indexed as

HumansQuality of LifeUrinary Bladder Neoplasms

Identifiers

PMID32504291
OpenAlexW3033638733

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.