Evidence map›Paper›PMID 32504222›Full record

ArticleInflammopharmacology2020

LP44 (4-[2-(methylthio)phenyl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1-piperazinehexanamide) exerts anti-ulcer effects via 5-hydroxytryptamine receptor 7 activation on indomethacin-induced gastric ulcers in rats.

Ilknur Calik, Muhammed Yayla, Irfan Cinar, Elif Cadirci, Abdulmecit Albayrak, Busra Sirin, Muhammet Calik, Zekai Halici

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Article in Inflammopharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Ilknur CalikDepartment of Pathology, Faculty of Medicine, Firat University, 23119, Elazıg, Turkey.
Muhammed YaylaDepartment of Pharmacology, Faculty of Medicine, Kafkas University, 36180, Kars, Turkey.
Irfan CinarDepartment of Pharmacology, Faculty of Medicine, Kafkas University, 36180, Kars, Turkey.
Elif CadirciDepartment of Pharmacology, Faculty of Medicine, Ataturk University, 25240, Erzurum, Turkey.
Abdulmecit AlbayrakDepartment of Pharmacology, Faculty of Medicine, Ataturk University, 25240, Erzurum, Turkey.
Busra SirinDepartment of Pharmacology, Faculty of Medicine, Ataturk University, 25240, Erzurum, Turkey.
Muhammet CalikDepartment of Pathology, Faculty of Medicine, Firat University, 23119, Elazıg, Turkey.
Zekai HaliciDepartment of Pharmacology, Faculty of Medicine, Ataturk University, 25240, Erzurum, Turkey. hzekai@atauni.edu.tr.ORCID http://orcid.org/0000-0001-6854-6059
Atatürk University · TRFırat University · TRKafkas University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThis study aimed to demonstrate the role of serotonin 7 receptor (5-HT MATERIAL AND

methodMale albino Wistar rats (n = 60) were used in the experiments. LP44 (5-HT

resultsWe analyzed the iNOS, eNOS, and 5-HT

conclusionThe study suggested that activation of 5-HT

Indexed as

AmidesAnimalsFamotidineGene ExpressionIndomethacinMaleNitric Oxide Synthase Type IIIPhenolsPiperazinesRatsRats, WistarReceptors, SerotoninRNA, MessengerSerotonin AntagonistsSerotonin Receptor AgonistsStomach UlcerAmidesFamotidineIndomethacinNitric Oxide Synthase Type IIIPhenolsPiperazinesReceptors, SerotoninRNA, MessengerSB 269970serotonin 7 receptorSerotonin AntagonistsSerotonin Receptor AgonistsSulfonamides5-HT7eNOSiNOSRatUlcer

Identifiers

PMID32504222
OpenAlexW3033896958

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.