Evidence map›Paper›PMID 32504127›Full record

ReviewCurrent psychiatry reports2020

Pharmacotherapy for Borderline Personality Disorder: an Update of Published, Unpublished and Ongoing Studies.

Jutta Stoffers-Winterling, Ole Jakob Storebø, Klaus Lieb

Open access · hybridAbstract readReview
In one paragraph

Review in Current psychiatry reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 80 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pharmacological interventions for self-harm in adults.The Cochrane database of systematic reviews · 2021
    Pooled it
  4. Trial
  5. A pilot randomized controlled trial of ketamine in Borderline Personality Disorder.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023
    Trial
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. MDMA-Assisted Psychotherapy for Borderline Personality Disorder.Focus (American Psychiatric Publishing) · 2022
    Review
  18. The societal cost of treatment-seeking patients with borderline personality disorder in Germany.European archives of psychiatry and clinical neuroscience · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Jutta Stoffers-WinterlingDepartment of Psychiatry and Psychotherapy, University Medical Center of the Johannes Gutenberg University Mainz, Untere Zahlbacher Straße 8, D-55131, Mainz, Germany. jutta.winterling@gmail.com.
Ole Jakob StorebøCenter for Evidence-Based Psychiatry, Psychiatric Research Unit, Slagelse, Region Zealand Psychiatry, Denmark.
Klaus LiebDepartment of Psychiatry and Psychotherapy, University Medical Center of the Johannes Gutenberg University Mainz, Untere Zahlbacher Straße 8, D-55131, Mainz, Germany.
Johannes Gutenberg University Mainz · DEUniversity Medical Center of the Johannes Gutenberg University Mainz · DEUniversity of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of the reviewWe aim to identify the most recent evidence of randomised controlled trials evaluating continued drug treatments in people with a diagnosis of BPD, review the most recent findings, highlight trends in terms of currently ongoing studies and comment on the overall body of evidence. RECENT

findingsWe identified seven new RCTs, plus newly available data for an older RCT. Only three of these RCTs have been published in full text, while we found study data posted at trial registry platforms for the others. The new findings do not support fluoxetine as a treatment option for suicide and self-harm prevention. A large effectiveness study did not detect beneficial effects of lamotrigine in routine care. The prevalent use of medications in BPD is still not reflected or supported by the current evidence. More research is needed regarding the most commonly used substances and substance classes, i.e. SSRIs, and quetiapine, but also with respect to people presenting with distinct comorbid conditions.

Indexed as

Borderline Personality DisorderSelf-Injurious BehaviorSuicideHumansLamotrigineRandomized Controlled Trials as TopicSelective Serotonin Reuptake InhibitorsLamotrigineSelective Serotonin Reuptake InhibitorsAnticonvulsantsAntidepressantsAntipsychoticsBorderline personality disorderDrug treatmentReview

Identifiers

PMID32504127
PMCPMC7275094
OpenAlexW3033743540

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.