Evidence map›Paper›PMID 32503997›Full record

ArticleNature communications2020

Robust dynamic community detection with applications to human brain functional networks.

L-E Martinet, M A Kramer, W Viles, L N Perkins, E Spencer, C J Chu, S S Cash, E D Kolaczyk

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 61 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

L-E Martinet *Department of Neurology, Massachusetts General Hospital, Boston, MA, 02114, USA.
M A Kramer *Department of Mathematics and Statistics, Boston University, Boston, MA, 02215, USA.ORCID http://orcid.org/0000-0002-9979-7202
W VilesDepartment of Mathematics and Statistics, Boston University, Boston, MA, 02215, USA.
L N PerkinsGraduate Program in Neuroscience, Boston University, Boston, MA, 02215, USA.ORCID http://orcid.org/0000-0002-4750-085X
E SpencerGraduate Program in Neuroscience, Boston University, Boston, MA, 02215, USA.ORCID http://orcid.org/0000-0001-9103-4561
C J ChuDepartment of Neurology, Massachusetts General Hospital, Boston, MA, 02114, USA.
S S CashDepartment of Neurology, Massachusetts General Hospital, Boston, MA, 02114, USA.
E D KolaczykDepartment of Mathematics and Statistics, Boston University, Boston, MA, 02215, USA. kolaczyk@bu.edu.ORCID http://orcid.org/0000-0002-3376-626X
Boston University · USMassachusetts General Hospital · US

Funding

Identification of Cortical Biomarkers for Seizure Risk in Childhood EpilepsyK23NS092923 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI CHU, CATHERINE J · 2015 to 2020
$1.0M
CRCNS: Dynamic network analysis of human seizures for therapeutic interventionR01NS095369 · NINDS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI CASH, SYDNEY S, KOLACZYK, ERIC D · 2015 to 2017
$950k
NINDS NIH HHS K23 NS092923NINDS NIH HHS R01 NS095369
6 · The paper itself

Abstract

While current technology permits inference of dynamic brain networks over long time periods at high temporal resolution, the detailed structure of dynamic network communities during human seizures remains poorly understood. We introduce a new methodology that addresses critical aspects unique to the analysis of dynamic functional networks inferred from noisy data. We propose a dynamic plex percolation method (DPPM) that is robust to edge noise, and yields well-defined spatiotemporal communities that span forward and backwards in time. We show in simulation that DPPM outperforms existing methods in accurately capturing certain stereotypical dynamic community behaviors in noisy situations. We then illustrate the ability of this method to track dynamic community organization during human seizures, using invasive brain voltage recordings at seizure onset. We conjecture that application of this method will yield new targets for surgical treatment of epilepsy, and more generally could provide new insights in other network neuroscience applications.

Indexed as

AdultAlgorithmsBrainComputer SimulationElectrodesHumansMaleNerve NetSeizuresTime Factors

Identifiers

PMID32503997
PMCPMC7275079
OpenAlexW3032922651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.