Evidence map›Paper›PMID 32503981›Full record

ArticleNature communications2020

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Hao Chen, Haibo Yang, Xiaolan Zhu, Tribhuwan Yadav, Jian Ouyang, Samuel S Truesdell, Jun Tan, Yumin Wang, Meihan Duan, Leizhen Wei and 4 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 133 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
133citing papers in PubMed, 2 pooled it
8.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

133 citing papers in PubMed, 2 syntheses or guidelines pooled it, 168 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. mBiology direct · 2026
    Review
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  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. RNA modification systems as therapeutic targets.Nature reviews. Drug discovery · 2026
    Review

73 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Hao Chen *Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, UPMC Hillman Cancer Center, 5117 Centre Ave., Pittsburgh, PA, 15213, USA.ORCID http://orcid.org/0000-0002-8377-9712
Haibo Yang *Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, 02129, USA.
Xiaolan Zhu *Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, 02129, USA.
Tribhuwan YadavDepartment of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02115, USA.
Jian OuyangMassachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, 02129, USA.
Samuel S TruesdellMassachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, 02129, USA.
Jun TanMassachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, 02129, USA.
Yumin WangDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, UPMC Hillman Cancer Center, 5117 Centre Ave., Pittsburgh, PA, 15213, USA.
Meihan DuanDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, UPMC Hillman Cancer Center, 5117 Centre Ave., Pittsburgh, PA, 15213, USA.
Leizhen WeiDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, UPMC Hillman Cancer Center, 5117 Centre Ave., Pittsburgh, PA, 15213, USA.
Lee ZouMassachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, 02129, USA.ORCID http://orcid.org/0000-0003-3094-1058
Arthur S LevineDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, UPMC Hillman Cancer Center, 5117 Centre Ave., Pittsburgh, PA, 15213, USA.
Shobha VasudevanMassachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, 02129, USA.
Li LanDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, UPMC Hillman Cancer Center, 5117 Centre Ave., Pittsburgh, PA, 15213, USA. llan1@mgh.harvard.edu.ORCID http://orcid.org/0000-0003-0383-6172
Harvard University · USUPMC Hillman Cancer Center · US

Funding

Regulation of the ATR Checkpoint Kinase by DNA DamageR01GM076388 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI ZOU, LEE · 2006 to 2018
$4.3M
Implications of the ATR Checkpoint Kinase in Radiation and Targeted TherapiesR01CA197779 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI ZOU, LEE · 2015 to 2020
$2.4M
Specialized post-transcriptional mechanisms of gene expression in quiescenceR35GM134944 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI VASUDEVAN, SHOBHA · 2020 to 2023
$1.8M
Post-transcriptional Gene Expression of the TNF alpha by an FXR1a-associated microRNPR01GM100202 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI VASUDEVAN, SHOBHA · 2015 to 2019
$1.7M
Transcription-Coupled Homologous Recombination upon DNA DamageR01GM118833 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LAN, LI · 2016 to 2020
$1.6M
Role of RNA methylation in chemoresistant cancer cellsR21CA220103 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI VASUDEVAN, SHOBHA · 2020 to 2021
$424k
NCI NIH HHS R01 CA197779NCI NIH HHS R21 CA220103NIGMS NIH HHS R01 GM076388NIGMS NIH HHS R01 GM100202NIGMS NIH HHS R01 GM118833NIGMS NIH HHS R35 GM134944
6 · The paper itself

Abstract

Recruitment of DNA repair proteins to DNA damage sites is a critical step for DNA repair. Post-translational modifications of proteins at DNA damage sites serve as DNA damage codes to recruit specific DNA repair factors. Here, we show that mRNA is locally modified by m

Indexed as

DNA Breaks, Double-StrandedHomologous RecombinationAnimalsCell Line, TumorCytosineDNA (Cytosine-5-)-MethyltransferasesDrug Resistance, NeoplasmGene Knockdown TechniquesHumansMethylationMiceNeoplasmsPoly(ADP-ribose) Polymerase InhibitorsRad51 RecombinaseRad52 DNA Repair and Recombination ProteinRNA, MessengerCytosineDNA (Cytosine-5-)-MethyltransferasesPoly(ADP-ribose) Polymerase InhibitorsRad51 RecombinaseRad52 DNA Repair and Recombination ProteinRAD52 protein, humanRNA, MessengerRNA, Small InterferingTRDMT1 protein, human

Identifiers

PMID32503981
PMCPMC7275041
OpenAlexW3033832055

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.