Evidence map›Paper›PMID 32503962›Full record

ArticleMedical science monitor : international medical journal of experimental and clinical research2020

Antimicrobial Activity of Nano-Magnesium Hydroxide Against Oral Bacteria and Application in Root Canal Sealer.

Yingying Meng, Dan Zhang, Xingya Jia, Keshen Xiao, Xiao Lin, Yi Yang, Dake Xu, Qiang Wang

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medical science monitor : international medical journal of experimental and clinical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Comparative antimicrobial activity of four different endodontic sealers.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Article
  9. Investigation of the Biosafety of Antibacterial Mg(OH)Journal of functional biomaterials · 2023
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Yingying MengSchool and Hospital of Stomatology, China Medical University, Shenyang, Liaoning, China (mainland).
Dan ZhangSchool and Hospital of Stomatology, China Medical University, Shenyang, Liaoning, China (mainland).
Xingya JiaSchool and Hospital of Stomatology, China Medical University, Shenyang, Liaoning, China (mainland).
Keshen XiaoInstitute of Metal Research, Chinese Academy of Sciences, Shenyang, Liaoning, China (mainland).
Xiao LinOrthopaedic Institute and Department of Orthopaedics, The First Affiliated Hospital, Soochow University, Suzhou, Jiangsu, China (mainland).
Yi YangKey Laboratory for Anisotropy and Texture of Materials, Northeastern University, Shenyang, Liaoning, China (mainland).
Dake XuKey Laboratory for Anisotropy and Texture of Materials, Northeastern University, Shenyang, Liaoning, China (mainland).
Qiang WangSchool and Hospital of Stomatology, China Medical University, Shenyang, Liaoning, China (mainland).
China Medical University · CNNortheastern University · CNChinese Academy of Sciences · CNFirst Affiliated Hospital of Soochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND The goal of the present work was to assess the antibacterial activity of nano-magnesium hydroxide (NMH) against Streptococcus mutans (S. mutans) and to explore the antimicrobial function of AH Plus™ sealer incorporating NMH. MATERIAL AND METHODS The antimicrobial behavior of NMH against S. mutans was evaluated with bactericidal tests. A modified direct contact test was used to assess the antimicrobial activity of unset AH Plus containing NMH after 5 minutes, 20 minutes, and 60 minutes of contact with bacteria. The antimicrobial effects and the amount of surface-adhering bacteria of the solidified materials were explored by SEM and confocal laser scanning microscopy, respectively. RESULTS NMH powder presented excellent antimicrobial activity against S. mutans. Mg²⁺ and OH⁻ were not the main factors resulting in bacterial death. Approximately 93.1% and 98% of the S. mutans were killed in the AH Plus+7% NMH group after incubation for 5 minutes and 20 minutes, respectively. AH Plus with 5% or 7% NMH were more potent against S. mutans compared with AH Plus alone (P<0.05). Moreover, the antibacterial function of AH Plus was lost after setting. NMH enabled the solidified AH Plus to still have antibacterial properties on the seventh day. CONCLUSIONS NMH can be used to modify AH Plus sealer to eradicate residual bacteria and prevent reinfection.

Indexed as

Anti-Bacterial AgentsAnti-Infective AgentsBiofilmsChinaHumansMagnesium HydroxideMaterials TestingMicrobiotaRoot Canal Filling MaterialsStreptococcus mutansZinc Oxide-Eugenol CementAnti-Bacterial AgentsAnti-Infective Agentscanals sealerMagnesium HydroxideRoot Canal Filling MaterialsZinc Oxide-Eugenol Cement

Identifiers

PMID32503962
PMCPMC7297022
OpenAlexW3015239240

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.