Evidence map›Paper›PMID 32503913›Full record

ArticleApplied and environmental microbiology2020

Comparative Target Analysis of Chlorinated Biphenyl Antimicrobials Highlights MenG as a Molecular Target of Triclocarban.

Robert Macsics, Mathias W Hackl, Christian Fetzer, Dietrich Mostert, Jennifer Bender, Franziska Layer, Stephan A Sieber

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Robert MacsicsChair of Organic Chemistry II, Technische Universität München, Garching bei München, Germany.
Mathias W HacklChair of Organic Chemistry II, Technische Universität München, Garching bei München, Germany.
Christian FetzerChair of Organic Chemistry II, Technische Universität München, Garching bei München, Germany.
Dietrich MostertChair of Organic Chemistry II, Technische Universität München, Garching bei München, Germany.
Jennifer BenderNational Reference Centre for Staphylococci and Enterococci, Robert Koch Institute, Wernigerode, Germany.ORCID 0000-0001-5167-3836
Franziska LayerNational Reference Centre for Staphylococci and Enterococci, Robert Koch Institute, Wernigerode, Germany.
Stephan A SieberChair of Organic Chemistry II, Technische Universität München, Garching bei München, Germany stephan.sieber@tum.de.ORCID 0000-0002-9400-906X
Technical University of Munich · DERobert Koch Institute · DEHelmholtz Centre for Infection Research · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triclocarban (TCC), a formerly used disinfectant, kills bacteria via an unknown mechanism of action. A structural hallmark is its

Indexed as

Bacterial ProteinsCarbanilidesDisinfectantsEnterococcusMethyltransferasesStaphylococcus aureusBacterial ProteinsCarbanilidesDisinfectantsMethyltransferasestriclocarbanantimicrobial agentsmechanisms of actionproteomicsStaphylococcus aureustriclocarbantriclosan

Identifiers

PMID32503913
PMCPMC7414967
OpenAlexW3033546169

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.