Evidence map›Paper›PMID 32503583›Full record

Observational studyBMC public health2020

Influence of quality of intensive care on quality of life/return to work in survivors of the acute respiratory distress syndrome: prospective observational patient cohort study (DACAPO).

Christian Apfelbacher, Susanne Brandstetter, Sebastian Blecha, Frank Dodoo-Schittko, Magdalena Brandl, Christian Karagiannidis, Michael Quintel, Stefan Kluge, Christian Putensen, Sven Bercker and 7 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 13 institutions in 1 country.

Christian ApfelbacherInstitute of Social Medicine and Health Systems Research, Medical Faculty, Otto von Guericke University Magdeburg, Leipziger Str. 44, 39120, Magdeburg, Germany. christian.apfelbacher@med.ovgu.de.ORCID http://orcid.org/0000-0003-3805-8219
Susanne BrandstetterMedical Sociology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, 93051, Regensburg, Germany.
Sebastian BlechaDepartment of Anesthesia & Operative Intensive Care, University Hospital Regensburg, 93042, Regensburg, Germany.
Frank Dodoo-SchittkoMedical Sociology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, 93051, Regensburg, Germany.
Magdalena BrandlMedical Sociology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, 93051, Regensburg, Germany.
Christian KaragiannidisDepartment of Pneumology and Critical Care Medicine, Cologne-Merheim Hospital, ARDS and ECMO Centre, Kliniken der Stadt Köln, Witten/Herdecke University Hospital, 51109, Cologne, Germany.
Michael QuintelDepartment of Anaesthesiology, Emergency and Intensive Care Medicine, University Medicine, 37075, Göttingen, Germany.
Stefan KlugeDepartment of Intensive Care Medicine, University Medical Centre, Hamburg-Eppendorf, 20246, Hamburg, Germany.
Christian PutensenDepartment of Anesthesiology and Operative Intensive Care, University Hospital Bonn, 53127, Bonn, Germany.
Sven BerckerDepartment of Anaesthesiology and Intensive Care Medicine, University Hospital Leipzig, 04103, Leipzig, Germany.
Björn EllgerDepartment of Anesthesiology and Intensive Care, Klinikum Dortmund, 44137, Dortmund, Germany.
Thomas KirschningDepartment of Anesthesiology and Intensive Care, University Hospital Mannheim, 68167, Mannheim, Germany.
Christian ArndtDepartment of Anesthesiology and Operative Intensive Care, University Hospital Marburg, 35042, Marburg, Germany.
Patrick MeybohmDepartment of Anesthesiology, Intensive Care Medicine, and Pain Therapy, University Hospital Würzburg, 97080, Würzburg, Germany.
Steffen Weber-CarstensDepartment of Anaesthesiology and Intensive Care Medicine, Charité -University Medicine Berlin, 10117, Berlin, Germany.
DACAPO study group
Thomas BeinDepartment of Anesthesia & Operative Intensive Care, University Hospital Regensburg, 93042, Regensburg, Germany. thomas.bein@ukr.de.
Universität Hamburg · DEUniversitätsmedizin Göttingen · DEUniversity Hospital Regensburg · DEHeidelberg University · DEPhilipps University of Marburg · DEUniversity of Regensburg · DEUniversitätsklinikum Würzburg · DECharité - Universitätsmedizin Berlin · DEKlinikum Dortmund · DEUniversity Hospital Bonn · DEUniversity Hospital Leipzig · DEWitten/Herdecke University · DEOtto-von-Guericke-Universität Magdeburg · DE

Funding

Bundesministerium für Bildung und Forschung 01GY1340
6 · The paper itself

Abstract

backgroundSignificant long-term reduction in health-related quality of life (HRQoL) is often observed in survivors of the acute respiratory distress syndrome (ARDS), and return to work (RtW) is limited. There is a paucity of data regarding the relationship between the quality of care (QoC) in the intensive care unit (ICU) and both HRQoL and RtW in ARDS survivors. Therefore, the aim of our study was to investigate associations between indicators of QoC and HRQoL and RtW in a cohort of survivors of ARDS.

methodsTo determine the influence of QoC on HRQoL and RtW 1 year after ICU-discharge, ARDS patients were recruited into a prospective multi-centre patient cohort study and followed up regularly after discharge. Patients were asked to complete self-report questionnaires on HRQoL (Short Form 12 physical component scale (PCS) and mental component scale (MCS)) and RtW. Indicators of QoC pertaining to volume, structural and process quality, and general characteristics were recorded on ICU level. Associations between QoC indicators and HrQoL and RtW were investigated by multivariable linear and Cox regression modelling, respectively. B values and hazard ratios (HRs) are reported with corresponding 95% confidence intervals (CIs).

results877 (of initially 1225 enrolled) people with ARDS formed the DACAPO survivor cohort, 396 were finally followed up to 1 year after discharge. The twelve-month survivors were characterized by a reduced HRQoL with a greater impairment in the physical component (Md 41.2 IQR [34-52]) compared to the mental component (Md 47.3 IQR [33-57]). Overall, 50% of the patients returned to work. The proportion of ventilated ICU patients showed significant negative associations with both 12 months PCS (B = - 11.22, CI -20.71; - 1,74) and RtW (HR = 0,18, CI 0,04;0,80). All other QoC indicators were not significantly related to outcome.

conclusionsAssociations between ICU QoC and long-term HrQoL and RtW were weak and largely non-significant. Residual confounding by case mix, treatment variables before or during ICU stay and variables pertaining to the post intensive care period (e.g. rehabilitation) cannot be ruled out.

trial registrationClinicaltrials.govNCT02637011. (December 22, 2015, retrospectively registered).

Indexed as

AdultCritical CareFemaleHumansIntensive Care UnitsMaleMiddle AgedPatient DischargeProspective StudiesQuality of Health CareQuality of LifeRespiratory Distress SyndromeReturn to WorkSurveys and QuestionnairesSurvivorsARDSHealth-related quality of lifeICUQuality of careReturn to workVolume

Identifiers

PMID32503583
PMCPMC7275400
OpenAlexW3034049350

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.