ArticleBMC plant biology2020
Transcription factor TabHLH49 positively regulates dehydrin WZY2 gene expression and enhances drought stress tolerance in wheat.
Article in BMC plant biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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32 citing papers in PubMed, 70 citations in OpenAlex.
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- Comprehensive analysis of ABA-aldehyde oxidase genes associated with drought and salt stress tolerance in wheat (Frontiers in plant science · 2026Article
- Comparative transcriptome analysis reveals abscisic acid-induced bHLH transcription factors involved in saikosaponin biosynthesis inPlant signaling & behavior · 2025Article
- bHLH Transcription Factors in Cereal Crops: Diverse Functions in Regulating Growth, Development and Stress Responses.International journal of molecular sciences · 2025Review
- Single-Cell Transcriptome Reveals the Cellular Response to PEG-Induced Stress in Wheat Leaves.Journal of agricultural and food chemistry · 2025Article
- Exploring the Role of TaERF4a in Enhancing Drought Tolerance and Regulating DehydrinPlants (Basel, Switzerland) · 2025Article
- Biochemical and gene expression profiling of five pear species under drought stress conditions.BMC plant biology · 2025Article
- The StbHLH47 transcription factor negatively regulates drought tolerance in potato (Solanum tuberosum L.).BMC plant biology · 2025Article
- Innovative opportunities for gene editing technology in crop breeding: from the perspective of literature analysis.Frontiers in plant science · 2025Article
- SlUPA-like, a bHLH Transcription Factor in Tomato (International journal of molecular sciences · 2024Article
- Mouse testicular macrophages can independently produce testosterone and are regulated by Cebpb.Biological research · 2024Article
- Genome-wide identification of bHLH transcription factors in Kenaf (Physiology and molecular biology of plants : an international journal of functional plant biology · 2024Article
- Genome-wide identification and expression analysis of bHLH gene family revealed their potential roles in abiotic stress response, anthocyanin biosynthesis and trichome formation inFrontiers in plant science · 2024Article
- Molecular mapping of two novel cold resistance genes in common wheat by 660K SNP array.Molecular breeding : new strategies in plant improvement · 2023Article
- Genome-Wide Characterization ofPlants (Basel, Switzerland) · 2023Article
- Improved pearl millet genomes representing the global heterotic pool offer a framework for molecular breeding applications.Communications biology · 2023Article
- Genome-wide identification and expression analysis of late embryogenesis abundant (Forestry research · 2023Article
- Association mapping unravels the genetics controlling seedling drought stress tolerance in winter wheat.Frontiers in plant science · 2023Article
- A Novel bHLH Transcription Factor PtrbHLH66 from Trifoliate Orange Positively Regulates Plant Drought Tolerance by Mediating Root Growth and ROS Scavenging.International journal of molecular sciences · 2022Article
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5 authors at 3 institutions in 1 country.
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Abstract
backgroundAs functional proteins, dehydrins are found in many maturing seeds and vegetable tissues under adverse environmental conditions. However, the regulation of dehydrin expression remains unclear.
resultsIn this study, a novel drought stress-related bHLH transcription factor, TabHLH49, was isolated from a wheat cDNA library treated with the drought and cold stress by using yeast one-hybrid system. TabHLH49 protein possesses a typical conserved bHLH domain and is a Myc-type bHLH transcription factor. TabHLH49 was detected in the nucleus of tobacco epidermal cells, and the amino acid sequences at the C-terminus (amino acids 323-362) is necessary for its transactivation activity. Real-time PCR analyses revealed the tissue-specific expression and drought stress-responsive expression of TabHLH49 in wheat. In addition, the verification in Y1H and electrophoretic mobility shift assays illustrated that TabHLH49 protein can bind and interact with the promoter of the wheat WZY2 dehydrin. Furthermore, the dual-luciferase assays showed that TabHLH49 can positively regulate the expression of WZY2 dehydrin. The transient expression and BSMV-mediated gene silencing of TabHLH49 also showed that TabHLH49 positively regulates the expression of WZY2 dehydrin and improves drought stress resistance in wheat.
conclusionsThese results provide direct evidences that TabHLH49 positively regulates expression level of dehydrin WZY2 gene and improves drought tolerance of wheat.
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