Evidence map›Paper›PMID 32503490›Full record

ArticleBMC cardiovascular disorders2020

Ventricular strain analysis in patients with no structural heart disease using a vendor-independent speckle-tracking software.

Hongmei Xia, Darwin F Yeung, Cristina Di Stefano, Stephen S Cha, Patricia A Pellikka, Zi Ye, Jeremy J Thaden, Hector R Villarraga

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC cardiovascular disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Observational
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Hongmei XiaDepartment of Ultrasound, Xinqiao Hospital, Third Military Medical University, Chongqing, China.
Darwin F YeungDepartment of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, 200 First St SW, Rochester, MN, 55905, USA.
Cristina Di StefanoHypertension Unit, Department of Medical Sciences, University of Torino, Torino, Italy.
Stephen S ChaDivision of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, USA.
Patricia A PellikkaDepartment of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, 200 First St SW, Rochester, MN, 55905, USA.
Zi YeDepartment of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, 200 First St SW, Rochester, MN, 55905, USA.
Jeremy J ThadenDepartment of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, 200 First St SW, Rochester, MN, 55905, USA.
Hector R VillarragaDepartment of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, 200 First St SW, Rochester, MN, 55905, USA. villarraga.hector@mayo.edu.ORCID 0000-0002-3675-6948
Mayo Clinic · USArmy Medical University · CNUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVentricular strain measurements vary depending on cardiac chamber (left ventricle [LV] or right ventricle [RV]), type of strain (longitudinal, circumferential, or radial), ventricular level (basal, mid, or apical), myocardial layer (endocardial or epicardial), and software used for analysis, among other demographic factors such as age and gender. Here, we present an analysis of ventricular strain taking all of these variables into account in a cohort of patients with no structural heart disease using a vendor-independent speckle-tracking software.

methodsLV and RV full-thickness strain parameters were retrospectively measured in 102 patients (mean age 39 ± 15 years; 62% female). Within this cohort, we performed further layer-specific strain analysis in 20 subjects. Data were analyzed for global and segmental systolic strain, systolic strain rate, early diastolic strain rate, and their respective time-to-peak values.

resultsMean LV global longitudinal, circumferential, and radial strain values for the entire cohort were - 18.4 ± 2.0%, - 22.1 ± 4.1%, and 43.9 ± 12.1% respectively, while mean RV global and free wall longitudinal strain values were - 24.2 ± 3.9% and - 26.1 ± 5.2% respectively. Women on average demonstrated higher longitudinal and circumferential strain and strain rate than men, and longer corresponding time-to-peak values. Longitudinal strain measurements were highest at the apex compared with the mid ventricle and base, and in the endocardium compared with the epicardium. Longitudinal strain was the most reproducible measure, followed closely by circumferential strain, while radial strain showed suboptimal reproducibility.

conclusionsWe present an analysis of ventricular strain in patients with no structural heart disease using a vendor-independent speckle-tracking software.

Indexed as

EchocardiographyImage Interpretation, Computer-AssistedVentricular Function, LeftVentricular Function, RightAdultDatabases, FactualDiastoleFemaleHeart VentriclesHumansMaleMiddle AgedPredictive Value of TestsReproducibility of ResultsRetrospective StudiesSoftware2D speckle-tracking echocardiographyMyocardial mechanicsStrain

Identifiers

PMID32503490
PMCPMC7275339
OpenAlexW3033161307

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.