ArticleBMC geriatrics2020
The association between a fracture risk tool and frailty: Geelong Osteoporosis Study.
Article in BMC geriatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Perioperative Considerations for Orthopedic Surgery in a Geriatric Population.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2026Review
- Association between physical function parameters and fracture risk in older women in primary health care in southern Brazil.Archives of osteoporosis · 2026Article
- Geriatric-Typical Characteristic Complexes Predict Short-Term Outcome of Proximal Humeral Fractures in Geriatric Patients.Clinical interventions in aging · 2026Article
- A comparison of content from across contemporary Australian population health surveys.Australian and New Zealand journal of public health · 2024Article
- Falls and fall-related injuries: prevalence, characteristics, and treatment among participants of the Geelong Osteoporosis Study.Frontiers in public health · 2024Article
- Effects of Frailty Syndrome on Osteoporosis, Focusing on the Mediating Effect of Muscle Strength and Balance in Community-Dwelling Older Adults (≥60 years) in Iran: Results From the Amirkola Health and Aging Project Cohort Study.Geriatric orthopaedic surgery & rehabilitation · 2024Article
- Frailty syndrome in women with osteoporosis, should physicians consider screening? A cross-sectional study.Bone reports · 2023Article
- Targeted optimum care approach for osteoporotic fragility fractures: tailored strategy based on risk stratification to reduce incidents of falls-an initiative by the Egyptian Academy of bone health based on the FLS national register.Archives of osteoporosis · 2023Observational
- Medical optimization of osteoporosis for adult spinal deformity surgery: a state-of-the-art evidence-based review of current pharmacotherapy.Spine deformity · 2023Review
- The Impact of Controlling Nutritional Status (CONUT) score on functional prognosis in hospitalized elderly patients with acute osteoporotic vertebral fractures.BMC geriatrics · 2022Article
- How Well Do Low Population-Specific Values for Muscle Parameters Associate with Indices of Poor Physical Health? Cross-Sectional Data from the Geelong Osteoporosis Study.Journal of clinical medicine · 2022Article
- Role of Fracture Risk Assessment Tool and Bone Turnover Markers in Predicting All-Cause and Cardiovascular Mortality in Hemodialysis Patients.Frontiers in medicine · 2022Article
- The contribution of musculoskeletal factors to physical frailty: a cross-sectional study.BMC musculoskeletal disorders · 2021Article
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Authors and funding
9 authors.
Funding
Abstract
backgroundFrailty is characterised by age-related declines in physical, psychological and social functioning. Features of frailty overlap with risk factors for fragility fractures. The aim of this study was to investigate the association between the fracture risk assessment tool (FRAX®) and frailty.
methodsIn cross-sectional analysis, frailty status was determined for participants aged 60-90 yr at 15-year follow-up of the Geelong Osteoporosis Study, using a modified Fried frailty phenotype. Using the FRAX on-line tool, scores for hip and major osteoporotic fracture (MOF) were calculated with and without bone mineral density (BMD). Using the area under Receiver Operating Characteristic (AUROC) curves, and FRAX scores calculated at the baseline visit for these participants, we investigated the association of FRAX and frailty 15 years later.
resultsForty-seven of 303 women (15.5%) and 41 of 282 men (14.5%) were frail at the 15-year visit. There was a gradient of increasing median FRAX scores from robust to frail. For example, for women, median MOF-FRAX without BMD increased from 5.9 for the robust to 7.5 for the pre-frail and 14.0 for the frail (p < 0.001). In secondary analyses, an association was observed between FRAX and frailty over 15 years, with the highest AUROC for women being 0.72 for MOF-FRAX with BMD, and for men, 0.76 hip-FRAX without BMD.
conclusionAn association was observed between FRAX and frailty where frail men and women had higher FRAX-scores compared to the other groups. Preliminary data suggest that FRAX, with or without BMD, may be useful in enhancing the information on frailty. Further research using larger datasets will be required to explore this.
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