Evidence map›Paper›PMID 32503329›Full record

ReviewInternational journal of molecular sciences2020

Nanocomposites for X-Ray Photodynamic Therapy.

Zaira Gadzhimagomedova, Peter Zolotukhin, Oleg Kit, Daria Kirsanova, Alexander Soldatov

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Mini Review On: The Roles of DNA Nanomaterials in Phototherapy.International journal of nanomedicine · 2025
    Review
  5. Review
  6. Article
  7. Review
  8. Biodegradable hafnium-doped CaCONanomedicine (London, England) · 2024
    Article
  9. Review
  10. Synthesis Optimization of BaGdFMaterials (Basel, Switzerland) · 2022
    Article
  11. Article
  12. Review
  13. Review
  14. The Physical Chemistry and Chemical Physics (PCCP) Section of theInternational journal of molecular sciences · 2021
    Article
  15. BaGdFInternational journal of molecular sciences · 2021
    Article
  16. The Rare-Earth Elements Doping of BaGdFNanomaterials (Basel, Switzerland) · 2021
    Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zaira GadzhimagomedovaThe Smart Materials Research Institute, Southern Federal University, 344090 Rostov-on-Don, Russia.
Peter ZolotukhinAcademy of Biology and Biotechnology, Southern Federal University, 344090 Rostov-on-Don, Russia.
Oleg KitDepartment of Oncology, National Medical Research Centre for Oncology, 344037 Rostov-on-Don, Russia.
Daria KirsanovaThe Smart Materials Research Institute, Southern Federal University, 344090 Rostov-on-Don, Russia.
Alexander SoldatovThe Smart Materials Research Institute, Southern Federal University, 344090 Rostov-on-Don, Russia.

Funding

Russian Science Foundation 19-15-00305
6 · The paper itself

Abstract

Photodynamic therapy (PDT) has long been known as an effective method for treating surface cancer tissues. Although this technique is widely used in modern medicine, some novel approaches for deep lying tumors have to be developed. Recently, deeper penetration of X-rays into tissues has been implemented, which is now known as X-ray photodynamic therapy (XPDT). The two methods differ in the photon energy used, thus requiring the use of different types of scintillating nanoparticles. These nanoparticles are known to convert the incident energy into the activation energy of a photosensitizer, which leads to the generation of reactive oxygen species. Since not all photosensitizers are found to be suitable for the currently used scintillating nanoparticles, it is necessary to find the most effective biocompatible combination of these two agents. The most successful combinations of nanoparticles for XPDT are presented. Nanomaterials such as metal-organic frameworks having properties of photosensitizers and scintillation nanoparticles are reported to have been used as XPDT agents. The role of metal-organic frameworks for applying XPDT as well as the mechanism underlying the generation of reactive oxygen species are discussed.

Indexed as

AnimalsCell Line, TumorHumansHydroxyl RadicalMetal-Organic FrameworksMiceNanocompositesNanoparticlesNanotechnologyNeoplasm TransplantationOxygenPhotochemotherapyPhotosensitizing AgentsReactive Oxygen SpeciesX-RaysHydroxyl RadicalMetal-Organic FrameworksOxygenPhotosensitizing AgentsReactive Oxygen Speciescancerphotodynamic therapyphotosensitizerreactive oxygen speechesscintillating nanoparticleX-ray photodynamic therapy

Identifiers

PMID32503329
PMCPMC7312431

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.